Results 241 to 250 of about 129,123 (307)

Combining single-molecule and structural studies reveals protein and DNA conformations and assemblies that govern DNA mismatch repair. [PDF]

Curr Opin Struct Biol
Erie DA, Weninger KR.
europepmc   +1 more source

Identification of Natural and Artificial Modifications in DNA at the Nanometer Level

Journal of Raman Spectroscopy, EarlyView.
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig, Prabha Singh, Miklos Veres, Roman Holomb, Volker Deckert   +4 more
wiley   +1 more source

MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma. [PDF]

Acta Neuropathol
Friker LL, Perwein T, Waha A, Dörner E, Klein R, Blattner-Johnson M, Layer JP, Sturm D, Nussbaumer G, Kwiecien R, Spier I, Aretz S, Kerl K, Hennewig U, Rohde M, Karow A, Bluemcke I, Schmitz AK, Reinhard H, Hernáiz Driever P, Wendt S, Weiser A, Guerreiro Stücklin AS, Gerber NU, von Bueren AO, Khurana C, Jorch N, Wiese M, Kratz CP, Eyrich M, Karremann M, Herrlinger U, Hölzel M, Jones DTW, Hoffmann M, Pietsch T, Gielen GH, Kramm CM.   +37 more
europepmc   +1 more source

Demographic and Clinical Characteristics of Early‐Onset Colorectal Cancer in Sweden and Finland: A Multicentre Retrospective Cohort Study Over Three Decades

Journal of Surgical Oncology, EarlyView.
ABSTRACT Colorectal cancer is the third most common cancer worldwide, and the proportion of individuals diagnosed under the age of 50 years, referred to as early‐onset colorectal cancer (EOCRC), is increasing. The aim of this study was to evaluate how the demographic and clinical features of EOCR in northern Sweden and Finland have changed over time ...
Melina Charalambidi, Tanja Hukkinen, Tuomas Kaprio, Sofia Edin, Mats Hjortborg, Cecilia Williams, Jaana Hagström, Caj Haglund, Richard Palmqvist, Karin Strigård, Camilla Böckelman, Ioannis Gkekas   +11 more
wiley   +1 more source

The ubiquitin ligase UBR4 and the deubiquitylase USP5 modulate the stability of DNA mismatch repair protein MLH1. [PDF]

J Biol Chem
Mao C, Li S, Che J, Liu D, Mao X, Rao H.
europepmc   +1 more source

Clinicopathological Significance of Defective DNA Mismatch Repair in Endometrial Carcinoma: A Single-Center Study From Bahrain. [PDF]

Cureus
Hammad M, Almahari SAI, Umakanth S, Toorani ZA.   +3 more
europepmc   +1 more source

Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer. [PDF]

Cell Rep Med
Nowak M, Jabbar F, Rodewald AK, Gneo L, Tomasevic T, Harkin A, Iveson T, Saunders M, Kerr R, Oein K, Maka N, Hay J, Edwards J, Tomlinson I, Sansom O, Kelly C, Pezzella F, Kerr D, Easton A, Domingo E, TransSCOT group, Koelzer VH, Church DN.   +22 more
europepmc   +1 more source

MutLα suppresses error-prone DNA mismatch repair and preferentially protects noncoding DNA from mutations. [PDF]

J Biol Chem
Kadyrova LY, Mieczkowski PA, Kadyrov FA.
europepmc   +1 more source

Response to immune checkpoint inhibition in a meningioma with DNA mismatch repair deficiency. [PDF]

Neurooncol Adv
Nguyen MP, Almiron Bonnin D, Mirchia K, Chen WC, Goldschmidt E, Braunstein SE, Perry A, Raleigh DR, Oberheim Bush NA.   +8 more
europepmc   +1 more source

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Eukaryotic DNA mismatch repair

Current Opinion in Genetics & Development, 1999
Eukaryotic mismatch repair (MMR) has been shown to require two different heterodimeric complexes of MutS-related proteins: MSH2-MSH3 and MSH2-MSH6. These two complexes have different mispair recognition properties and different abilities to support MMR. Alternative models have been proposed for how these MSH complexes function in MMR.
R D, Kolodner, G T, Marsischky
openaire   +2 more sources