Results 11 to 20 of about 8,812 (165)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1. [PDF]

Adv Sci (Weinh)
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Jiang N, Jin S, Wen S, Zeng W, Wang C, Wang J, Song Q, Li G, Yin P, Liao Y, Chai Y, Zhang H, Ma S.   +12 more
europepmc   +2 more sources

Characterization of DNA binding activities of over-expressedKpnI restriction endonuclease and modification methylase [PDF]

Journal of Biosciences, 1999
The genes encoding theKpnI restriction endonuclease and methyltransferase fromKlebsiella pneumoniae have been cloned and expressed inEscherchia coli using a two plasmid strategy. The gene forKpnI methylase with its promoter was cloned and expressed in pACYC184. Even though the methylase clone is in a low copy number plasmid pACMK, high level expression
Chandrashekaran, Siddamadappa, Babu, Padmanabhan, Nagaraja, Valakunja   +2 more
openaire   +2 more sources

DNA methylase modifications and other linezolid resistance mutations in coagulase-negative staphylococci in Italy [PDF]

Journal of Antimicrobial Chemotherapy, 2010
Despite 10 years of clinical use, linezolid resistance in Staphylococcus aureus and coagulase-negative staphylococci (CoNS) is still a rare phenomenon. This study reports the mechanisms of resistance and strain types seen in clusters of linezolid-resistant CoNS from two different hospitals in Italy during the period 2008-09.Genes associated with ...
BONGIORNO D, CAMPANILE, FLORIANA, MONGELLI G, BALDI MT, PROVENZANI R, REALI S, LO RUSSO C, SANTAGATI, Maria Carmela, STEFANI, Stefania   +8 more
openaire   +4 more sources

The EcoRV Modification Methylase Causes Considerable Bending of DNA upon Binding to Its Recognition Sequence GATATC [PDF]

Journal of Biological Chemistry, 1996
The EcoRV methyltransferase modifies DNA by the introduction of a methyl group at the 6-NH2 position of the first deoxyadenosine in GATATC sequences. The enzyme forms a stable and specific complex with GATATC sequences in the presence of a nonreactive analogue, such as sinefungin, of its natural cofactor S-adenosyl-L-methionine.
S, Cal, B A, Connolly
openaire   +2 more sources

DNA adenine methylase, not the PstI restriction-modification system, regulates virulence gene expression in Shiga toxin-producing Escherichia coli

Food Microbiology, 2021
We previously reported a distinct methylome between the two Shiga toxin-producing Escherichia coli (STEC) O145:H28 strains linked to the 2010 U.S. lettuce-associated outbreak (RM13514) and the 2007 Belgium ice cream-associated outbreak (RM13516), respectively.
Michelle Qiu Carter, Antares Pham, Steven Huynh, Craig T. Parker, Avalon Miller, Xiaohua He, Bin Hu, Patrick S.G. Chain   +7 more
openaire   +2 more sources

Cloning and characterization of the HpaII methylase gene [PDF]

, 1990
The HpaII restriction-modification system from Haemophilus parainfluenzae recognizes the DNA sequence CCGG. The gene for the HpaII methylase has been cloned into E. coli and its nucleotide sequence has been determined.
Card, C. O., Wilson, G. G., Weule, K., Hasapes, J., Kiss, A., Roberts, R. J.   +5 more
core   +1 more source

Phylogeographic evidence of cognate recognition site patterns and transformation efficiency differences in H. pylori: theory of strain dominance [PDF]

, 2013
BACKGROUND: Helicobacter pylori has diverged in parallel to its human host, leading to distinct phylogeographic populations. Recent evidence suggests that in the current human mixing in Latin America, European H.
Ana Maldonado-Contreras, Bodo Linz, Luis Pericchi, Martin J Blaser, María Domínguez-Bello, Monica Contreras, Shrinivasrao P Mane, Teresa Alarcón, Xue-Song Zhang   +8 more
core   +2 more sources

The sequence specificity domain of cytosine-C5 methylases [PDF]

, 1991
Prokaryotic DNA[cytosine-C5]methyltransferases (m5C-methylases) share a common architectural arrangement of ten conserved sequence motifs. A series of eleven hybrids have been constructed between the HpaII (recognition sequence: Cm5CGG) and HhaI ...
Klimasauskas, S., Nelson, J. L., Roberts, R. J.   +2 more
core   +1 more source

Cfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells [PDF]

, 2014
BackgroundTrimethylation of histone H3 lysine 4 (H3K4me3) accumulates at promoters in a gene activity dependent manner. The Set1 complex is responsible for most H3K4me3 in somatic cells and contains the conserved subunit Cfp1, which is implicated in ...
Bird, Adrian, Clouaire, Thomas, Webb, Shaun   +2 more
core   +1 more source

Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases

BMC Research Notes, 2010
Background NruI and Sbo13I are restriction enzyme isoschizomers with the same recognition sequence 5' TCG↓CGA 3' (cleavage as indicated↓). Here we report the cloning of NruI and Sbo13I restriction-modification (R-M) systems in E. coli.
Benner Jack, Fomenkov Alexey, Pedamallu Chandra, Zhu Zhenyu, Xu Shuang-yong   +4 more
doaj   +1 more source