Results 1 to 10 of about 43,846 (273)
ON THE SPECIFICITY OF DNA POLYMERASE [PDF]
Proceedings of the National Academy of Sciences, 1967 Elisabeth Bautz Freese, Ernst Freese
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Nobel Prize laureate Kary Mullis and the polymerase chain reaction (PCR) [PDF]
The Ukrainian Biochemical Journal, 2021 The article highlights the major life and career milestones and the extraordinary personality of 1993 Nobel Prize laureate in Chemistry Kary B. Mullis.
V. M. Danilova +2 more
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Frontiers in Bioengineering and Biotechnology, 2021 A change of an aspartic acid to asparagine of Taq (Thermus aquaticus) DNA polymerase is a gain of function mutation that supports faster PCR: the extension times for PCR amplification can be 2–3 times shorter.
Wayne M. Barnes +3 more
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International Journal of Molecular Sciences, 2019 Maintenance of genome integrity is a key process in all organisms. DNA polymerases (Pols) are central players in this process as they are in charge of the faithful reproduction of the genetic information, as well as of DNA repair. Interestingly, all eukaryotes possess a large repertoire of polymerases.
Jose-Antonio Pedroza-Garcia +2 more
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Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity [PDF]
Open Biology, 2017 During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in vitro replication assay, PolC is the main polymerase while the lagging strand DnaE polymerase ...
Vasileios Paschalis +5 more
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DNA polymerases in Biotechnology [PDF]
Frontiers in Microbiology, 2014 Accurate duplication of parental DNA is a fundamental biological process, conserved in function across all life forms. All organisms depend on DNA polymerases for genome replication and maintenance. DNA polymerases also play central roles in modern molecular biology and biotechnology, enabling techniques including DNA cloning, the polymerase chain ...
Gardner, Andrew F., Kelman, Zvi
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Jurnal Entomologi Indonesia, 2022 Identification based on molecular character of Nucleopolyhedrovirusin Helicoverpa armigera Hubner (Lepidoptera: Noctuidae) larvae from Bogor, West Java.
R. Yayi Munara Kusumah +2 more
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DNA polymerase III protein, HolC, helps resolve replication/transcription conflicts
Microbial Cell, 2021 In Escherichia coli, DNA replication is catalyzed by an assembly of proteins, the DNA polymerase III holoenzyme. This complex includes the polymerase and proofreading subunits, the processivity clamp and clamp loader complex.
Susan T. Lovett
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Polymerase Mu Is a DNA-Directed DNA/RNA Polymerase [PDF]
Molecular and Cellular Biology, 2003 DNA polymerases are defined as such because they use deoxynucleotides instead of ribonucleotides with high specificity. We show here that polymerase mu (pol μ), implicated in the nonhomologous end-joining pathway for repair of DNA double-strand breaks, incorporates both ribonucleotides and deoxynucleotides in a template-directed manner.
Stephanie A. Nick McElhinny +1 more
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International Journal of Technology, 2020 Access to biological engineering has become a critical point of modern science development through polymerase chain reaction (PCR). One of the main components in this process is DNA polymerase, which copies the main template DNA.
Kenny Lischer +5 more
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