REBASE--restriction enzymes and DNA methyltransferases [PDF]
Nucleic Acids Research, 2004 REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in restriction–modification. It contains both published and unpublished work with information about recognition and cleavage
Richard J. Roberts
semanticscholar +8 more sources
Structures of the type I DNA restriction enzymes. [PDF]
Proc Natl Acad Sci U S A, 2017 The article by Liu et al. (1) on the structure of type I DNA restriction and modification enzymes purports to significantly advance our understanding of these enzymes and proposes a model for their operation.
Dryden DTF.
europepmc +6 more sources
Structure and operation of the DNA-translocating type I DNA restriction enzymes. [PDF]
Genes Dev, 2012 Type I DNA restriction/modification (RM) enzymes are molecular machines found in the majority of bacterial species. Their early discovery paved the way for the development of genetic engineering.
Kennaway CK +15 more
europepmc +8 more sources
Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI [PDF]
Nucleic Acids Research, 2006 Many restriction enzymes require binding of two copies of a recognition sequence for DNA cleavage, thereby introducing a loop in the DNA. We investigated looping dynamics of Type IIE restriction enzymes NaeI and NarI by tracking the Brownian motion of ...
Bram van den Broek +4 more
semanticscholar +9 more sources
A physical map of human Alu repeats cleavage by restriction endonucleases [PDF]
BMC Genomics, 2008 Background Alu repetitive elements are the abundant sequences in human genome. Diversity of DNA sequences of these elements makes difficult the construction of theoretical patterns of Alu repeats cleavage by restriction endonucleases.
Chernukhin Valery A +3 more
doaj +5 more sources
NEBcutter: a program to cleave DNA with restriction enzymes [PDF]
Nucleic Acids Research, 2003 NEBcutter, version 1.0, is a program available via a web server (http://tools.neb.com/NEBcutter) that will accept an input DNA sequence and produce a comprehensive report of the restriction enzymes that will cleave the sequence.
Tamas Vincze, J. Posfai, R. Roberts
semanticscholar +3 more sources
Fused
BMC Evolutionary Biology, 2011 Background The discovery of restriction endonucleases and modification DNA methyltransferases, key instruments of genetic engineering, opened a new era of molecular biology through development of the recombinant DNA technology.
Solonin Alexander S +2 more
doaj +4 more sources
Straightforward Procedure for Laboratory Production of DNA Ladder [PDF]
Journal of Nucleic Acids, 2012 DNA ladder is commonly used to determine the size of DNA fragments by electrophoresis in routine molecular biology laboratories. In this study, we report a new procedure to prepare a DNA ladder that consists of 10 fragments from 100 to 1000 bp.
Vo Thi Thuong Lan +5 more
doaj +4 more sources
REBASE—enzymes and genes for DNA restriction and modification [PDF]
Nucleic Acids Research, 2007 REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification.
R. Roberts +3 more
semanticscholar +4 more sources
Highlights of the DNA cutters: a short history of the restriction enzymes [PDF]
Nucleic Acids Research, 2013 In the early 1950’s, ‘host-controlled variation in bacterial viruses’ was reported as a non-hereditary phenomenon: one cycle of viral growth on certain bacterial hosts affected the ability of progeny virus to grow on other hosts by either restricting or ...
W. Loenen +4 more
semanticscholar +5 more sources