Structures of the type I DNA restriction enzymes. [PDF]
Proc Natl Acad Sci U S A, 2017 The article by Liu et al. (1) on the structure of type I DNA restriction and modification enzymes purports to significantly advance our understanding of these enzymes and proposes a model for their operation.
Dryden DTF.
europepmc +6 more sources
REBASE—restriction enzymes and DNA methyltransferases [PDF]
Nucleic Acids Research, 2004 REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in restriction–modification. It contains both published and unpublished work with information about recognition and cleavage
R. Roberts +3 more
semanticscholar +5 more sources
Structure and operation of the DNA-translocating type I DNA restriction enzymes. [PDF]
Genes Dev, 2012 Type I DNA restriction/modification (RM) enzymes are molecular machines found in the majority of bacterial species. Their early discovery paved the way for the development of genetic engineering.
Kennaway CK +15 more
europepmc +8 more sources
NEBcutter: a program to cleave DNA with restriction enzymes [PDF]
Nucleic Acids Research, 2003 NEBcutter, version 1.0, is a program available via a web server (http://tools.neb.com/NEBcutter) that will accept an input DNA sequence and produce a comprehensive report of the restriction enzymes that will cleave the sequence.
Tamas Vincze, J. Posfai, R. Roberts
semanticscholar +3 more sources
REBASE—enzymes and genes for DNA restriction and modification [PDF]
Nucleic Acids Research, 2007 REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification.
R. Roberts +3 more
semanticscholar +4 more sources
Highlights of the DNA cutters: a short history of the restriction enzymes [PDF]
Nucleic Acids Research, 2013 In the early 1950’s, ‘host-controlled variation in bacterial viruses’ was reported as a non-hereditary phenomenon: one cycle of viral growth on certain bacterial hosts affected the ability of progeny virus to grow on other hosts by either restricting or ...
W. Loenen +4 more
semanticscholar +5 more sources
Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences. [PDF]
PLoS ONE, 2019 Restriction enzymes recognize and bind to specific sequences on invading bacteriophage DNA. Like a key in a lock, these proteins require many contacts to specify the correct DNA sequence.
Thomas D Schneider, Vishnu Jejjala
doaj +2 more sources
Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. [PDF]
Nucleic Acids Research, 2000 This study concerns chimeric restriction enzymes that are hybrids between a zinc finger DNA-binding domain and the non-specific DNA-cleavage domain from the natural restriction enzyme FOK:I.
Jeffrey S. Smith +6 more
semanticscholar +2 more sources
REBASE—a database for DNA restriction and modification: enzymes, genes and genomes [PDF]
Nucleic Acids Research, 2014 REBASE is a comprehensive and fully curated database of information about the components of restriction-modification (RM) systems. It contains fully referenced information about recognition and cleavage sites for both restriction enzymes and ...
R. Roberts +3 more
semanticscholar +6 more sources
The average spacing of restriction enzyme recognition sites in DNA [PDF]
Journal of Theoretical Biology, 1982 The discovery of naturally occurring enzymes which cleave DNA at sites specific to particular nucleotide sequences has had a great impact on molecular biology. The function of these enzymes in uivo is to protect bacterial cells from viral invasion by degradation of foreign DNA.
Gordon P. Moore, A. R. Moore
openalex +5 more sources