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Fluctuations and Supercoiling of DNA

Science, 1994
Frequently, DNA in vivo is organized into loops that are partially underwound and consequently form interwound helical supercoils. Methods from polymer statistical mechanics are used to show how the competition between entropy (thermal fluctuations) and elastic energy determines supercoil radius and pitch, in good agreement with recent experiments and ...
J F, Marko, E D, Siggia
openaire   +2 more sources

Supercoiling transitions of closed DNA

Physical Review E, 1994
Conformations of closed DNA molecules are considered within a simple elastic model. The interplay of elastic energies of bending and twisting can lead to supercoiling induced by variations of the linking difference. These shape transformations are studied in the limit of a large length to thickness ratio of the molecule.
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Local Supercoil-Stabilized DNA Structure

Critical Reviews in Biochemistry and Molecular Biology, 1991
The DNA double helix exhibits local sequence-dependent polymorphism at the level of the single base pair and dinucleotide step. Curvature of the DNA molecule occurs in DNA regions with a specific type of nucleotide sequence periodicities. Negative supercoiling induces in vitro local nucleotide sequence-dependent DNA structures such as cruciforms, left ...
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PICH and TOP3A cooperate to induce positive DNA supercoiling

Nature Structural & Molecular Biology, 2019
Anna H. Bizard   +6 more
semanticscholar   +1 more source

DNA Supercoiling

2004
Chris R. Calladine   +3 more
openaire   +2 more sources

DNA Supercoiling

Biochemical Society Transactions, 1986
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Topoisomerase-modulated genome-wide DNA supercoiling domains colocalize with nuclear compartments and regulate human gene expression

Nature Structural & Molecular Biology
Qian Yao   +4 more
semanticscholar   +1 more source

Supercoiled DNA

Journal of Chemical Education, 1986
openaire   +1 more source

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