Results 81 to 90 of about 8,858 (210)

Percentage of ATP-DnaA protein in cells with 2 x DnaA.

, 2015
1) Measured by western blot2) Number derived from [24]Percentage of ATP-DnaA protein in cells with 2 x DnaA.
Riikka Taipale (750567), Silje Martinsen (750568), Kirsten Skarstad (183763), Solveig Fossum-Raunehaug (647783), Ingvild Flåtten (183759)   +4 more
core   +1 more source

Targeting synthesis of the Chromosome Replication Initiator Protein DnaA by antisense PNA-peptide conjugates in Escherichia coli

Frontiers in Antibiotics
Initiation of chromosome replication is an essential stage of the bacterial cell cycle that is controlled by the DnaA protein. With the aim of developing novel antimicrobials, we have targeted the initiation of DNA replication, using antisense peptide ...
Christopher Campion, Christopher Campion, Godefroid Charbon, Peter E. Nielsen, Anders Løbner-Olesen   +4 more
doaj   +1 more source

“Expanding the Lactococcal Cell Wall Polysaccharide Paradigm: Novel Structures and Metabolic Pathways in the Emerging Dairy Species Pseudolactococcus laudensis and Pseudolactococcus raffinolactis”

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study characterizes the genetic diversity of Pseudolactococcus laudensis and Pseudolactococcus raffinolactis regarding cell wall polysaccharides (CWPS) and exopolysaccharide (EPS) biosynthesis, uncovering novel genotypes and biosynthetic pathways.
Axel Soto‐Serrano, Irina Sadovskaya, Evgeny Vinogradov, Wenwen Li, Jun‐Hyeok Yu, Kelsey White, Douwe van Sinderen, Lukasz Krych, Paulina Deptula, Jennifer Mahony   +9 more
wiley   +1 more source

Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome

, 2006
Initiation of DNA replication in Eschericia coli requires the ATP-bound form of the DnaA protein. The conversion of DnaA-ATP to DnaA-ADP is facilitated by a complex of DnaA, Hda (homologous to DnaA), and DNA-loaded beta-clamp proteins in a process termed
Marinus, Martin G., Riber, Leise, Dasgupta, Santanu,, Olsson, Jan A.,, Skovgaard, Ole, Jensen, Rasmus B., Løbner-Olesen, Anders   +6 more
core   +1 more source

Characterization of Staphylococcus aureus Primosomal DnaD Protein: Highly Conserved C-Terminal Region Is Crucial for ssDNA and PriA Helicase Binding but Not for DnaA Protein-Binding and Self-Tetramerization. [PDF]

PLoS ONE, 2016
The role of DnaD in the recruitment of replicative helicase has been identified. However, knowledge of the DNA, PriA, and DnaA binding mechanism of this protein for the DnaA- and PriA-directed replication primosome assemblies is limited. We characterized
Yen-Hua Huang, Yi Lien, Chien-Chih Huang, Cheng-Yang Huang   +3 more
doaj   +1 more source

Genome‐Driven Analysis Reveals the Biotechnological Potential of a Novel Paenibacillus sp. Isolated From Crude Oil

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The novel Paenibacillus sp. strain 210, isolated from Brazilian crude oil, its genome encoding 259 carbohydrate‐active enzymes for degrading cellulose, xylan, and pectin, positioning it as a candidate for biofuel production. The strain harbors complete pathways for B‐vitamin biosynthesis and antimicrobial biosynthetic clusters (e.g., fusaricidin and ...
João Victor dos Anjos Almeida, Carlos Miguel Nóbrega Mendonça, Leandro Marcio Moreira, Ricardo Pinheiro de Souza Oliveira, Alessandro de Mello Varani, Mauro de Medeiros Oliveira   +5 more
wiley   +1 more source

Rv0004 is a new essential member of the mycobacterial DNA replication machinery. [PDF]

PLoS Genetics, 2017
DNA replication is fundamental for life, yet a detailed understanding of bacterial DNA replication is limited outside the organisms Escherichia coli and Bacillus subtilis.
Katherine M Mann, Deborah L Huang, Anna J Hooppaw, Michelle M Logsdon, Kirill Richardson, Hark Joon Lee, Jacqueline M Kimmey, Bree B Aldridge, Christina L Stallings   +8 more
doaj   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras, Yann Quesnelle, Suzanne Trancart, Didier Goux, Jean‐Louis Blin, Manuel Savary, Maryline Houssin, Céline Zatylny‐Gaudin   +7 more
wiley   +1 more source

Comparison of DnaA boxes from a consensus sequence with DnaA boxes from the PSSM.

, 2015
(A) A logo, drawn using WebLogo [32], of the DnaA boxes used to construct the DnaA box PSSM is shown. (B-E) Histograms of the number of sequence reads that start at each nucleotide are plotted (blue for sequence reads mapping to the top strand; green for
Alan D. Grossman (237649), Janet L. Smith (213446)   +1 more
core   +1 more source

Allele specific synthetic lethality between priC and dnaA^ts alleles at the permissive temperature of 30°C in E. coli K-12

BMC Microbiology, 2004
Background DnaA is an essential protein in the regulation and initiation of DNA replication in many bacteria. It forms a protein-DNA complex at oriC to which DnaC loads DnaB.
Sandler Steven J, Hinds Tania
doaj   +1 more source