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Unique and Universal Features of Epsilonproteobacterial Origins of Chromosome Replication and DnaA-DnaA Box Interactions [PDF]

open access: yesFrontiers in Microbiology, 2016
In bacteria, chromosome replication is initiated by the interaction of the initiator protein DnaA with a defined region of a chromosome at which DNA replication starts (oriC).
Rafal Donczew   +2 more
exaly   +4 more sources

In-vitro helix opening of M. tuberculosis oriC by DnaA occurs at precise location and is inhibited by IciA like protein. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: Mycobacterium tuberculosis (M.tb), the pathogen that causes tuberculosis, is capable of staying asymptomatically in a latent form, persisting for years in very low replicating state, before getting reactivated to cause active infection. It is
Sandeep Kumar   +2 more
doaj   +1 more source

Whole-Genome Analysis Reveals That the Nucleoid Protein IHF Predominantly Binds to the Replication Origin oriC Specifically at the Time of Initiation

open access: yesFrontiers in Microbiology, 2021
The structure and function of bacterial chromosomes are dynamically regulated by a wide variety of nucleoid-associated proteins (NAPs) and DNA superstructures, such as DNA supercoiling.
Kazutoshi Kasho   +5 more
doaj   +1 more source

Development and host compatibility of plasmids for two important ruminant pathogens, Mycoplasma bovis and Mycoplasma agalactiae. [PDF]

open access: yesPLoS ONE, 2015
Mycoplasma bovis is a cause of pneumonia, mastitis, arthritis and otitis media in cattle throughout the world. However, despite its clinical significance, there is a paucity of tools to genetically manipulate it, impeding our capacity to further explore ...
Shukriti Sharma   +5 more
doaj   +1 more source

Ori-Finder 2022: A Comprehensive Web Server for Prediction and Analysis of Bacterial Replication Origins

open access: yesGenomics, Proteomics & Bioinformatics, 2022
The replication of DNA is a complex biological process that is essential for life. Bacterial DNA replication is initiated at genomic loci referred to as replication origins (oriCs).
Mei-Jing Dong, Hao Luo, Feng Gao
doaj   +1 more source

Mutations of DnaA-boxes in the oriR region increase replication frequency of the MiniR1–1 plasmid

open access: yesBMC Microbiology, 2018
Background The MiniR1–1 plasmid is a derivative of the R1 plasmid, a low copy cloning vector. Results Nucleotide sequencing analysis shows that the MiniR1–1 plasmid is a 6316 bp circular double-stranded DNA molecule with an oriR1 (origin for replication).
Yuan Yao   +4 more
doaj   +1 more source

Structure and Function of the Campylobacter jejuni Chromosome Replication Origin

open access: yesFrontiers in Microbiology, 2018
Campylobacter jejuni is the leading bacterial cause of foodborne infections worldwide. However, our understanding of its cell cycle is poor. We identified the probable C.
Pawel Jaworski   +5 more
doaj   +1 more source

The DnaA Tale

open access: yesFrontiers in Microbiology, 2018
More than 50 years have passed since the presentation of the Replicon Model which states that a positively acting initiator interacts with a specific site on a circular chromosome molecule to initiate DNA replication. Since then, the origin of chromosome
Flemming G. Hansen, Tove Atlung
doaj   +1 more source

Initiation of chromosomal replication in predatory bacterium Bdellovibrio bacteriovorus

open access: yesFrontiers in Microbiology, 2016
Bdellovibrio bacteriovorus is a small Gram-negative predatory bacterium that attacks other Gram-negative bacteria, including many animal, human, and plant pathogens.
Lukasz Makowski   +4 more
doaj   +1 more source

DNA replication origins in archaea

open access: yesFrontiers in Microbiology, 2014
DNA replication initiation, which starts at specific chromosomal site (known as replication origins), is the key regulatory stage of chromosome replication.
Zhenfang eWu   +5 more
doaj   +1 more source

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