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Mycoplasma agassizii Multilocus Sequence Typing Using Nanopore Sequencing: Insights Into Genetic Diversity and Isolate Characterization. [PDF]

open access: yesAnn N Y Acad Sci
ABSTRACT Mycoplasma agassizii (Mycoplasmopsis agassizii) is a major pathogen responsible for upper respiratory tract disease (URTD) in tortoises, contributing to worldwide population declines. Despite its significance, tools for strain‐level identification and epidemiological tracking remain limited.
Cacciotto C   +9 more
europepmc   +2 more sources

Impact of the GouM transporter on secondary metabolism activation and production yield in Streptomyces noursei strain CK‐15

open access: yesNew Plant Protection, Volume 3, Issue 3, September 2026.
Overexpression of the gouM transporter gene in Streptomyces noursei CK‐15 enhances gougerotin production by 114% and activates silent biosynthetic gene clusters. This finding links transporter activity to metabolite efflux and secondary metabolism, offering a strategy for natural product discovery and strain optimization.
Qianying Zhou   +6 more
wiley   +1 more source

Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract In bacteria, DnaB replicative helicases are essential for unwinding genomic DNA to provide the single‐stranded templates required for replication. The recruitment of the hexameric DnaB helicase to the origin of replication is mediated by distinct mechanisms that rely on specialized factors known as helicase loaders. The DciA family of helicase
Daniele Mazzoletti   +8 more
wiley   +1 more source

In Situ Bacterioplankton Growth Partitioning by High‐Resolution Metatranscriptomics

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Bacterial growth and primary production are key ecological indicators, yet often measured in bulk. Using metatranscriptomics, the authors identify FtsZ expression to track dividing cells (A, B). Phylogenetic placement of transcripts (C–E) enables linking growth activity to specific taxa (E, F), potentially bridging bulk measurements with fine‐scale ...
J. Cesar Ignacio‐Espinoza   +5 more
wiley   +1 more source

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller   +6 more
wiley   +1 more source

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo   +6 more
wiley   +1 more source

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan   +8 more
wiley   +1 more source

Diffusion Coefficients for Resonant Relativistic Wave‐Particle Interactions Using the PIRAN Code

open access: yesEarth and Space Science, Volume 13, Issue 3, March 2026.
Abstract Quasilinear diffusion coefficients can be used to model the response of charged particles to resonant wave‐particle interactions. The calculation of these coefficients is sufficiently complicated and arduous to render it prohibitive to many potential users, because of the expense in time spent developing the code.
Oliver Allanson   +12 more
wiley   +1 more source

Capillary‐Based Physicochemical Characterization of Lipid Nanoparticles

open access: yesELECTROPHORESIS, Volume 46, Issue 21, Page 1588-1599, November 2025.
ABSTRACT Lipid nanoparticles (LNPs) are widely used for the delivery of nucleic acid (NAs), most notably in gene therapy and messenger ribonucleic acid (mRNA)‐based vaccines. Understanding their physicochemical properties is essential, yet current analytical approaches often fall short in capturing their complexity.
Evrim Ümit Kuzucu   +3 more
wiley   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

open access: yesAdvanced Functional Materials, Volume 35, Issue 37, September 11, 2025.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen   +17 more
wiley   +1 more source

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