Results 21 to 30 of about 2,074 (98)
Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research
Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.This article provides an overview over antibacterial drugs investigated in the past three decades. Aspects of the compound's origins, their cellular targets, the antibacterial spectrum and proof‐of‐concept in animal studies are covered and current trends are highlighted.
Roderich D. Süssmuth +3 more
wiley +1 more source
Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure
Molecular Microbiology, Volume 123, Issue 3, Page 279-293, March 2025.Polyphosphate condensates and their contributions to nucleoid structure. Polyphosphate condensates form in the ribosome‐depleted nucleoid region of bacterial cells, particularly under stress (in this case Pseudomonas aeruginosa undergoing nitrogen starvation; adapted with permission from (Racki et al. 2017)). This Perspective explores the emerging view
Lisa R. Racki, Lydia Freddolino
wiley +1 more source
Intrinsic bent DNA sites in the chromosomal replication origin of Xylella fastidiosa 9a5c
Brazilian Journal of Medical and Biological Research, 2008 The features of the nucleotide sequences in both replication and promoter regions have been investigated in many organisms. Intrinsically bent DNA sites associated with transcription have been described in several prokaryotic organisms.
F. Gimenes +3 more
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Rok from B. subtilis: Bridging genome structure and transcription regulation
Molecular Microbiology, Volume 123, Issue 2, Page 109-123, February 2025.In our review on the dual role of B. subtilis Rok as genome organizer and gene regulator, we argue that these two functions are in fact two sides of the same coin and that the coupling between them should be taken into account in further research. We also propose a list of characteristics to aid in determining whether a protein belongs to the H‐NS‐like
Amanda M. Erkelens +3 more
wiley +1 more source
Assessing the Efficiency of Bin‐Centered Solid Waste Segregation System in Ashanti Region, Ghana
The Scientific World Journal, Volume 2025, Issue 1, 2025.Kwame Nkrumah University of Science and Technology (KNUST) established a waste segregation system that provided plastic waste to feed a plastic recycling facility to improve solid waste management in 2017. However, since the establishment of the segregation system, there has not been any assessment to ascertain its efficiency.
Lyndon N. A. Sackey +8 more
wiley +1 more source
Enhancing dietary analysis: Using machine learning for food caloric and health risk assessment
Journal of Food Science, Volume 89, Issue 11, Page 8006-8021, November 2024.Abstract In the wake of growing concerns regarding diet‐related health issues, this study investigates the application of machine learning methods to estimate the energy content and classify the health risks of foods based on the USDA National Nutrient Database.
Toby A. Adjuik +2 more
wiley +1 more source
Current Protocols, Volume 4, Issue 10, October 2024.Abstract Vibrio fischeri is a model mutualist for studying molecular processes affecting microbial colonization of animal hosts. We present a detailed protocol for a barcode sequencing (BarSeq) approach that combines targeted gene deletion with short‐read sequencing technology to enable studies of mixed bacterial populations. This protocol includes wet
Hector L. Burgos, Mark J. Mandel
wiley +1 more source
DNA Hierarchical Superstructures from Micellar Units: Stiff Hydrogels and Anisotropic Nanofibers
Chemistry – A European Journal, Volume 30, Issue 53, September 19, 2024.Using three different orthogonal interactions – hydrophobic effect, RNA kissing loops, DNA base pairing – we created hierarchical nanostructures from precise DNA amphiphiles. These micron‐sized materials are controlled by the nanoscale structure of the self‐assembled amphiphiles with sequence‐dependent behavior and have found applications as self ...
Michael D. Dore +5 more
wiley +1 more source
Protein Science, Volume 33, Issue 8, August 2024.Abstract Rhodanese‐like domains (RLDs) represent a widespread protein family canonically involved in sulfur transfer reactions between diverse donor and acceptor molecules. RLDs mediate these transsulfuration reactions via a transient persulfide intermediate, created by modifying a conserved cysteine residue in their active sites.
Robert Benisch, Tobias W. Giessen
wiley +1 more source
Putative Cooperative ATP-DnaA Binding to Double-Stranded DnaA Box and Single-Stranded DnaA-Trio Motif upon Helicobacter pylori Replication Initiation Complex Assembly. [PDF]
Int J Mol Sci, 2021 Jaworski P +6 more
europepmc +1 more source