Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production [PDF]
The objective of this study was to investigate membrane fatty acids for their effects on mitochondrial function in live cells. Mitochondrial potential and oxidant production were measured in human colonic adenocarcinoma (HT-29) cells with membranes ...
Steven M. Watkins+2 more
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Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease [PDF]
There is a need to develop interventions to slow or reverse the degeneration of dopamine neurons in Parkinson’s disease after diagnosis. Given that preclinical and clinical studies suggest benefits of dietary n-3 polyunsaturated fatty acids, such as ...
Olivier Kerdiles+10 more
doaj +2 more sources
Docosahexaenoic acid transfer into human milk after dietary supplementation: a randomized clinical trial [PDF]
Docosahexaenoic acid (DHA) is important for infant development. The DHA transfer from maternal diet into human milk has not been investigated in detail.
Nataša Fidler+4 more
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Molecular dynamic of omega-3 compounds as an anti-obesity agent into GPR-120 receptor [PDF]
Obesity is a cause of comorbid diseases such as type 2 diabetes mellitus, dyslipidemia, hypertension which is based on low-level chronic inflammation. The GPR-120 receptor plays a role in insulin sensitization which is related to diabetes mellitus which ...
Ida Musfiroh+4 more
doaj +3 more sources
Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. [PDF]
Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's disease.
Giuseppe Astarita+7 more
doaj +1 more source
Eicosapentaenoic acid and docosahexaenoic acid are two types of omega-3 fatty acids that provide numerous health benefits. It is thus important to gain the recommended daily intake of eicosapentaenoic acid and docosahexaenoic acid and compensate for ...
Hawra Abdulhussain+7 more
doaj +1 more source
Background: Currently, 1–2% of all prosthetic joint surgeries are followed by an infection. These infections cause approximately 4% of deaths in the first year after surgery, while the 5-year mortality rate is up to 21%.
Christopher Spiegel+2 more
doaj +1 more source
Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. [PDF]
Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a novel pro-resolving product, 13R,14S-dihydroxy-docosahexaenoic acid (13R,14S-diHDHA ...
Bin Deng+6 more
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Inexpensive carbon sources offering an alternative to glucose are searched for to reduce costs of docosahexaenoic acid production by microalgae. The use of waste glycerol seems substantiated and prospective in this case.
Natalia Kujawska+4 more
doaj +1 more source
Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementation
Lipids comprize from 50-60% of the structural matter of the brain and docosahexaenoic acid (C22:6, DHA) is the most important omega-3 long-chain polyunsaturated fatty acid in the brain phospholipids comprizing 25% of the total fatty acids of the grey ...
Alfonso Valenzuela+2 more
doaj +1 more source