In order to understand the mechanisms by which fatty acids are taken up by the placenta, the uptake of oleic, linoleic, arachidonic, and docosahexaenoic acids by cultured human placental choriocarcinoma (BeWo) cells was examined.
F M Campbell+4 more
doaj
Toxic effects of formaldehyde and the protective effect of docosahexaenoic acid in Drosophila
Formaldehyde (FA) is a commercially important chemical applied in industry and scientific research. However, FA has a distinct impact on learning and memory.
Hua Yanli+8 more
doaj +1 more source
Untangling direct and domain-mediated interactions between nicotinic acetylcholine receptors in DHA-rich membranes [PDF]
At the neuromuscular junction (NMJ), the nicotinic acetylcholine receptor (nAChR) self-associates to give rise to rapid muscle movement. While lipid domains have maintained nAChR aggregates in-vitro, their specific roles in nAChR clustering are currently unknown. In the present study, we carried out coarse-grained molecular dynamics simulations (CG-MD)
arxiv
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona+2 more
wiley +1 more source
Bioactive food components and their inhibitory actions in multiple platelet pathways
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das+7 more
wiley +1 more source
Impact of genotype on EPA and DHA status and responsiveness to increased intakes [PDF]
At a population level, cardioprotective and cognitive actions of the fish oil (FO) derived long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been extensively demonstrated.
Anne Minihane+9 more
core +2 more sources
Boundary lipids of the nicotinic acetylcholine receptor: spontaneous partitioning via coarse-grained molecular dynamics simulation [PDF]
Reconstituted nicotinic acetylcholine receptors (nAChRs) exhibit significant gain-of-function upon addition of cholesterol to reconstitution mixtures, and cholesterol affects organization of nAChRs within domain-forming membranes, but whether nAChR partitions to cholesterol-rich liquid-ordered ("raft" or $l_o$) domains or cholesterol-poor liquid ...
arxiv
Carbon Doping of MgB2 by Toluene and Malic-Acid-in-Toluene [PDF]
The decomposition of malic acid in the presence of Mg and B was studied using Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA) which revealed that malic acid reacted with Mg but not B. Also, the addition of toluene to dissolve malic acid followed by subsequent drying resulted in no reaction with Mg, indicating that the malic
arxiv +1 more source
Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda+2 more
wiley +1 more source
Abstract Background Racehorses commonly develop evidence of mild asthma in response to dust exposure. Diets deficient in omega‐3 polyunsaturated fatty acids (Ω‐3) might exacerbate this response. Hypothesis To compare dust exposure, bronchoalveolar lavage fluid (BALF) cytology, and plasma Ω‐3 and specialized pro‐resolving mediators (SPM) concentrations ...
Carla J. Olave+5 more
wiley +1 more source