Associations Between Fatty Acid Levels in Human Blood and Trigeminovascular Tissues
ABSTRACT Omega‐3 and omega‐6 polyunsaturated fatty acids (PUFAs) are precursors to oxylipins that modulate pain and inflammation. We previously demonstrated that (1) a dietary intervention increasing omega‐3 and reducing omega‐6 PUFAs alters the concentration of these oxylipin precursors in blood, and (2) these changes are associated with reduced ...
Daisy Zamora +8 more
wiley +1 more source
Amyloid-beta peptide, oxidative stress and inflammation in Alzheimer’s disease: Potential neuroprotective effects of omega-3 polyunsaturated fatty acids [PDF]
Alzheimer’s disease is the most common form of dementia in the elderly and is a progressive neurodegenerative disorder characterised by a decline in cognitive function and also profound alterations in mood and behaviour. The pathology of the disease is
Dyall, Simon
core +3 more sources
Measuring Peripheral Tissue DHA Turnover Using a Novel 13C Enrichment Technique
ABSTRACT Recently, through the use of compound‐specific isotope analysis (CSIA), our lab validated the utility of 13C enrichment (δ13C) of docosahexaenoic acid (DHA) by using a very high δ13C in a diet switch study by measuring brain, liver, and plasma DHA turnover and half‐lives via high‐precision gas chromatography combustion isotope ratio mass ...
Brinley J. Klievik +3 more
wiley +1 more source
Exploring the Role of Polyunsaturated Fatty Acids in Children’s Sleep
Research on the effects of polyunsaturated fatty acids on children’s sleep has made significant advancements. This study explores the unique pathways through which polyunsaturated fatty acids, particularly docosahexaenoic acid and eicosapentaenoic acid ...
Liuyan Zhu, Bingquan Zhu, Dan Yao
doaj +1 more source
Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]
Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland +16 more
core +2 more sources
Cashew Nut Oil Improves Lipid Metabolism and Fat Liver Deposition in High‐Fat Diet‐Fed C57BL/6J Mice
Thirty C57BL/6J mice were fed a high‐fat diet for 12 weeks to induce metabolic changes. They were then switched to diets containing cashew nut oil, soybean oil, or lard for another 12 weeks. Soybean oil reduced blood glucose, total cholesterol, LDL cholesterol, triglycerides, and liver steatosis.
Marcella Duarte Villas Mishima +11 more
wiley +1 more source
Docosahexaenoic acid: membrane modification and neurotrophic mechanisms
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids. Maintenance of a high DHA concentration in brain is essential for proper neuronal function, suggesting a unique requirement of this fatty acid for an ...
Kim Hee-Yong
doaj +1 more source
Blooms of filamentous cyanobacteria reduce zooplankton quality and pelagic food web efficiency
Abstract Cyanobacterial blooms in marine and freshwater ecosystems have increased in magnitude, frequency, and distribution worldwide during recent decades. Filamentous cyanobacteria are of unsuitable size for mesozooplankton feeding and of poorer nutritional quality than other phytoplankton taxa. The production and quality of higher trophic levels are
Tharindu Bandara +10 more
wiley +1 more source
Statistical Workflow for Feature Selection in Human Metabolomics Data. [PDF]
High-throughput metabolomics investigations, when conducted in large human cohorts, represent a potentially powerful tool for elucidating the biochemical diversity underlying human health and disease.
Antonelli, Joseph +17 more
core +2 more sources
Supplementary Figure 2 from Regulation of Colorectal Cancer Cell Apoptosis by the n-3 Polyunsaturated Fatty Acids Docosahexaenoic and Eicosapentaenoic [PDF]
Anna Girós +11 more
openalex +1 more source

