Results 121 to 130 of about 48,919 (268)
G protein‐coupled receptor‐mediated autophagy in health and disease
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan +2 more
wiley +1 more source
Journal of Lipid Research, 1994 The effect of different fatty acids on cytochrome P4504A1 mRNA levels was studied in primary cultures of rat hepatocytes, using a solution hybridization assay. All fatty acids tested induced P4504A1 mRNA levels in a dose- and time-dependent manner.
P Tollet +4 more
doaj
Effects of Docosahexaenoic and Eicosapentaenoic Acid on Lipid Metabolism, Eicosanoid Production, Platelet Aggregation and Atherosclerosis in Hypercholesterolemic Rats [PDF]
, 1999 Yosef Adan +4 more
openalex +1 more source
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel +11 more
wiley +1 more source
Effect of Docosahexaenoic Acid on the Synthesis of Phosphatidylserine in Rat Brain Microsomes and C6 Glioma Cells [PDF]
, 1998 Martha C. Garcia +4 more
openalex +1 more source
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
Cell Proliferation, EarlyView.One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye +6 more
wiley +1 more source
Functional Modulation of Human Recombinant γ-Aminobutyric Acid Type A Receptor by Docosahexaenoic Acid [PDF]
, 1998 Junichi Nabekura +4 more
openalex +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Metabolic‐associated steatotic liver disease (MASLD) is a prevalent chronic liver condition associated with significant morbidity and mortality. Effective pharmacological interventions targeting liver steatosis and fibrosis are essential to improving patient outcomes.
Jiaxin Zhong +3 more
wiley +1 more source
Dietary Docosahexaenoic Acid Dose Not Promote Lipid Peroxidation in Rat Tissue to the Extent Expected from Peroxidizability Index of the Lipids [PDF]
, 1998 Kazuhiro Kubo +3 more
openalex +1 more source