Results 21 to 30 of about 5,212,695 (327)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementation

Grasas y Aceites, 2006
Lipids comprize from 50-60% of the structural matter of the brain and docosahexaenoic acid (C22:6, DHA) is the most  important omega-3 long-chain polyunsaturated fatty acid in the brain phospholipids comprizing 25% of the total fatty acids of the grey ...
Alfonso Valenzuela, B. Julio Sanhueza, Susana Nieto   +2 more
doaj   +1 more source

Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease [PDF]

, 2014
Background: There are plausible mechanisms for how dietary docosahexaenoic acid (DHA), an n−3 polyunsaturated fatty acid, could prevent Crohn's disease (CD).
Abraham, Ananthakrishnan, Ananthakrishnan, Ananthakrishnan, Arita, Bartoli, Belluzzi, Bingham, Burdge, Chan, Charpentier, Corey, Depner, Feagan, Fritsche, Goldbohm, Goldman, Hommes, Jostins, Kaaks, Levy, Novak, Rao, Riboli, Rodriguez-Lagunas, Sakamoto, Salem, Samuelsson, Serhan, Serini, Shivananda, Tjonneland, Turner, Watanabe, Weylandt, Yaqoob   +35 more
core   +1 more source

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid

Journal of Lipid Research, 1995
The purpose of this study was to determine whether the formation of docosahexaenoic acid in human cells occurs through a pathway that involves 24-carbon n-3 fatty acid intermediates and retroconversion.
S A Moore, E Hurt, E Yoder, H Sprecher, A A Spector   +4 more
doaj   +1 more source

Effect of diet on the rate of depletion of n–3 fatty acids in the retina of the guinea pig

Journal of Lipid Research, 1998
This study has assessed the influence of maternal n–3 long chain polyunsaturated fatty acid supply and dietary manipulation after weaning on the retinal polyunsaturated fatty acid profile.
Harrison S. Weisinger, Algis J. Vingrys, Lavinia Abedin, Andrew J. Sinclair   +3 more
doaj   +1 more source

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim, Illig, Thomas, Koletzko, Berthold, Lattka, Eva   +3 more
core   +1 more source

Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells

Scientific Reports, 2018
The implication of inflammation in pathophysiology of several type of cancers has been under intense investigation. Omega-3 fatty acids can modulate inflammation and present anticancer effects, promoting cancer cell death.
N. Pizato, Beatriz Christina Luzete, Larissa Fernanda Melo Vasconcelos Kiffer, L. H. Corrêa, Igor de Oliveira Santos, José A F Assumpção, M. Ito, K. Magalhães   +7 more
semanticscholar   +1 more source

Uptake of long chain fatty acids by human placental choriocarcinoma (BeWo) cells: role of plasma membrane fatty acid-binding protein

Journal of Lipid Research, 1997
In order to understand the mechanisms by which fatty acids are taken up by the placenta, the uptake of oleic, linoleic, arachidonic, and docosahexaenoic acids by cultured human placental choriocarcinoma (BeWo) cells was examined.
F M Campbell, A M Clohessy, M J Gordon, K R Page, A K Dutta-Roy   +4 more
doaj   +1 more source

Docosahexaenoic Acid and Preterm Birth [PDF]

Annals of Nutrition and Metabolism, 2016
Preterm birth accounts for more than 85% of all perinatal complications and deaths. There are many short- and long-term consequences of being born too soon. These infants often require intensive care and are at increased risk of early morbidities often with life-long sequelae.
Makrides, M., Best, K.
openaire   +3 more sources

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Demmelmair, Hans, Fidler, N., Koletzko, Berthold, Pohl, A., Sauerwald, T.   +4 more
core   +1 more source