Docosahexaenoic Acid and the Aging Brain [PDF]
The Journal of Nutrition, 2008 The dietary essential PUFA docosahexaenoic acid [DHA; 22:6(n-3)] is a critical contributor to cell structure and function in the nervous system, and deficits in DHA abundance are associated with cognitive decline during aging and in neurodegenerative disease.
Nicolas G. Bazan, Walter J. Lukiw
openaire +3 more sources
Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease [PDF]
, 2014 Background: There are plausible mechanisms for how dietary docosahexaenoic acid (DHA), an n−3 polyunsaturated fatty acid, could prevent Crohn's disease (CD).
Abraham +35 more
core +1 more source
Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementation
Grasas y Aceites, 2006 Lipids comprize from 50-60% of the structural matter of the brain and docosahexaenoic acid (C22:6, DHA) is the most important omega-3 long-chain polyunsaturated fatty acid in the brain phospholipids comprizing 25% of the total fatty acids of the grey ...
Alfonso Valenzuela +2 more
doaj +1 more source
Energies, 2021 Inexpensive carbon sources offering an alternative to glucose are searched for to reduce costs of docosahexaenoic acid production by microalgae. The use of waste glycerol seems substantiated and prospective in this case.
Natalia Kujawska +4 more
doaj +1 more source
Diurnal rhythm of plasma EPA and DHA in healthy adults [PDF]
, 2020 Knowledge of the diurnal variation in circulating omega-3 polyunsaturated fatty acids (n-3 PUFAs) may be an important consideration for the development of dosing protocols designed to optimise tissue delivery of these fatty acids.
Avery, Hannah +7 more
core +2 more sources
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Comparison of different dietary sources of n-3 polyunsaturated fatty acids on immune response in broiler chickens [PDF]
, 2020 The study aims to research the effects of varied dietary sources of n-3 polyunsaturated fatty acids (PUFA) on the immune response in broiler chickens with stress on natural killer (NK) cell activity. Diets supplemented with one of the four sources of n-3
Al-Khalaifah, H. +4 more
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Amyloid-beta peptide, oxidative stress and inflammation in Alzheimer’s disease: Potential neuroprotective effects of omega-3 polyunsaturated fatty acids [PDF]
, 2010 Alzheimer’s disease is the most common form of dementia in the elderly and is a progressive neurodegenerative disorder characterised by a decline in cognitive function and also profound alterations in mood and behaviour. The pathology of the disease is
Dyall, Simon
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Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells [PDF]
, 2014 The roles of CYP lipid-metabolizing pathways in endothelial cells are poorly understood. Human endothelial cells expressed CYP2J2 and soluble epoxide hydrolase (sEH) mRNA and protein.
Ara A. Askari +35 more
core +1 more source
Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells
Scientific Reports, 2018 The implication of inflammation in pathophysiology of several type of cancers has been under intense investigation. Omega-3 fatty acids can modulate inflammation and present anticancer effects, promoting cancer cell death.
N. Pizato +7 more
semanticscholar +1 more source