Results 71 to 80 of about 48,919 (268)

Untangling direct and domain-mediated interactions between nicotinic acetylcholine receptors in DHA-rich membranes [PDF]

arXiv, 2019
At the neuromuscular junction (NMJ), the nicotinic acetylcholine receptor (nAChR) self-associates to give rise to rapid muscle movement. While lipid domains have maintained nAChR aggregates in-vitro, their specific roles in nAChR clustering are currently unknown. In the present study, we carried out coarse-grained molecular dynamics simulations (CG-MD)
arxiv  

Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology

ChemBioChem, EarlyView.
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda, Mario van der Stelt, Sander Izaak van Kasteren   +2 more
wiley   +1 more source

Boundary lipids of the nicotinic acetylcholine receptor: spontaneous partitioning via coarse-grained molecular dynamics simulation [PDF]

arXiv, 2018
Reconstituted nicotinic acetylcholine receptors (nAChRs) exhibit significant gain-of-function upon addition of cholesterol to reconstitution mixtures, and cholesterol affects organization of nAChRs within domain-forming membranes, but whether nAChR partitions to cholesterol-rich liquid-ordered ("raft" or $l_o$) domains or cholesterol-poor liquid ...
arxiv  

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source

The impact of 60 days of ‐6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Reductions in skeletal muscle mitochondrial respiration following 60 days of bed rest explained by a decrease in mitochondrial content, but resulting in an increase in OPA1 and Drp1 mediated mitochondrial fission. Abstract It is unclear how skeletal muscle metabolism and mitochondrial function adapt to long duration bed rest and ...
John Noone, Anthony Damiot, Helena Kenny, Isabelle Chery, Alexandre Zahariev, Sylvie Normand, François Crampes, Isabelle de Glisezinski, Keith D. Rochfort, Claire Laurens, Marie‐Pierre Bareille, Chantal Simon, Audrey Bergouignan, Stéphane Blanc, Donal J. O'Gorman   +14 more
wiley   +1 more source

Toxic effects of formaldehyde and the protective effect of docosahexaenoic acid in Drosophila

Translational Neuroscience, 2021
Formaldehyde (FA) is a commercially important chemical applied in industry and scientific research. However, FA has a distinct impact on learning and memory.
Hua Yanli, Ma Chao, Huang Shuyi, Wang Ruomeng, Chen Jian, Guo Qing, Zhou Jiaojiao, Zhu Hemin, Li Wenjie   +8 more
doaj   +1 more source

Acid zeta function and ajoint acid zeta function [PDF]

arXiv, 2010
In this paper we set up the theory of acid zeta function and ajoint acid zeta function, based on the theory, we point out a reason to doubt the truth of the Riemann hypothesis and also as a consequence, we give out some new RH equivalences.
arxiv  

Polymerisation and Oxidation of Docosahexaenoic Acid [PDF]

American Journal of Biochemistry and Biotechnology, 2016
Oils rich in polyunsaturated fatty acids, such as linseed oil, can oxidise to form polymers. These can be used as protective coatings and act as an alternative to those derived from petrochemicals. Such renewable source oils usually require the addition of metal ions as catalysts of the polymerisation process and/or the partial pre-oxidation of the oil
Shelly Lynn Browning, Brian M. Ross, Adrian McKee   +2 more
openaire   +2 more sources

Chemo‐Enzymatic Synthesis of Mixed Docosahexaenoic Acid Phosphatidylcholine Conjugates

European Journal of Organic Chemistry, EarlyView.
An efficient chemo‐enzymatic synthesis method is proposed for the production of mixed DHA (Docosahexaenoic acid) phosphatidylcholines, allowing access to both regioisomers with DHA positioned at either the sn1 or sn2 site. Regioisomers of acetate derivatives (AceDoPC®, DoAcePC, stabilized forms of LPC‐DHA) and phenolic‐DHA‐PCs (antioxidant drugs) were ...
Jordan Lehoux, Felix Grosjean, Alexandre Lobo, Michel Lagarde, Nathalie Bernoud‐Hubac, Thierry Durand, Celine Crauste   +6 more
wiley   +1 more source

Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat

Journal of Lipid Research, 1993
Dietary triglycerides containing predominantly poly-unsaturated fatty acids (PUFAs) are known to reduce plasma total and low density lipoprotein (LDL) cholesterol concentrations relative to triglycerides containing predominantly saturated fatty acids ...
DK Spady
doaj