Results 201 to 210 of about 77,870 (288)
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto +16 more
wiley +1 more source
ABSTRACT Headwater streams receive large amounts of terrestrial organic matter (tOM) such as leaves from a dense riparian matrix, forming a critical link between terrestrial and aquatic ecosystems. Terrestrial OM rarely provides essential macronutrients such as polyunsaturated fatty acids (PUFAs), and microbial colonisation of tOM is an important ...
Mourine J. Yegon +3 more
wiley +1 more source
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source
ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury
ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
wiley +1 more source
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Circulating fatty acid profiles and risk of pulmonary arterial hypertension: Evidence from a large prospective cohort study. [PDF]
Liu S +5 more
europepmc +1 more source
ABSTRACT Brain development is an ongoing process that occurs throughout the first 1000 days of life (conception until 2 years) and proceeds throughout childhood, adolescence and up until early adulthood. Adequate nutrient intakes are crucial for both neurodevelopment inside the womb and critical life‐stages thereafter when the brain continues to grow ...
Emma J. Derbyshire
wiley +1 more source
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka +6 more
wiley +1 more source
The effect of eicosapentaenoic and docosahexaenoic acids on physical function, exercise, and joint replacement in patients with coronary artery disease: A secondary analysis of a randomized clinical trial. [PDF]
Alfaddagh A +5 more
europepmc +1 more source

