Results 201 to 210 of about 77,870 (288)

Long‐term effects of a multidomain intervention on cognitive function and metabolic control in older adults with type 2 diabetes and mild cognitive impairment: A 42‐month follow‐up of the J‐MIND‐Diabetes study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2350-2361, March 2026.
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto   +16 more
wiley   +1 more source

Apparent Flexibility of Fatty Acid Metabolism in Shredders Depends on Terrigenous Organic Matter Type

open access: yesFreshwater Biology, Volume 71, Issue 3, March 2026.
ABSTRACT Headwater streams receive large amounts of terrestrial organic matter (tOM) such as leaves from a dense riparian matrix, forming a critical link between terrestrial and aquatic ecosystems. Terrestrial OM rarely provides essential macronutrients such as polyunsaturated fatty acids (PUFAs), and microbial colonisation of tOM is an important ...
Mourine J. Yegon   +3 more
wiley   +1 more source

Sex Differences in Metabolite–Immune Circuits of Neuroinflammation

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan   +6 more
wiley   +1 more source

ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
wiley   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

Eggs and Associated Nutrients: Implications for Brain Development and Function From Conception to Early Adulthood: A Narrative Review

open access: yesNutrition Bulletin, Volume 51, Issue 1, Page 46-66, March 2026.
ABSTRACT Brain development is an ongoing process that occurs throughout the first 1000 days of life (conception until 2 years) and proceeds throughout childhood, adolescence and up until early adulthood. Adequate nutrient intakes are crucial for both neurodevelopment inside the womb and critical life‐stages thereafter when the brain continues to grow ...
Emma J. Derbyshire
wiley   +1 more source

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

open access: yesPlant Biotechnology Journal, Volume 24, Issue 3, Page 1359-1376, March 2026.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka   +6 more
wiley   +1 more source

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