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Bioactive metabolites of docosahexaenoic acid

Biochimie, 2017
Docosahexaenoic acid (DHA) is an essential fatty acid that is recognized as a beneficial dietary constituent and as a source of the anti-inflammatory specialized proresolving mediators (SPM): resolvins, protectins and maresins. Apart from SPMs, other metabolites of DHA also exert potent biological effects.
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Immunomodulation of microglia by docosahexaenoic acid and eicosapentaenoic acid

Current Opinion in Clinical Nutrition and Metabolic Care, 2012
The omega-3 fatty acids (ω-3 FAs) docosahexaenoic acid and eicosapentaenoic acid are dietary components which have been ascribed many different health benefits. Inflammation is present in, and contributes to, pathological conditions in the central nervous system (CNS).
Erik, Hjorth, Yvonne, Freund-Levi
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Docosahexaenoic acid therapy in docosahexaenoic acid‐deficient patients with disorders of peroxisomal biogenesis

Lipids, 1996
AbstractA patient with classic Zellweger syndrome was treated with docosahexaenoic acid ethyl ester (DHA‐EE) for three months. Five other patients with Zellweger variants (four of them less than one‐year‐old and a five‐year‐old) were treated with DHA‐EE until normalization of the DHA levels in erythrocytes.
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The cardiovascular protective role of docosahexaenoic acid

European Journal of Pharmacology, 1996
Dietary fish oils rich in n-3 polyunsaturated fatty acids can modulate a diverse range of factors contributing to cardiovascular disease. This study examined the relative roles of eicosapentaenoic acid (20:5 n-3; EPA) and docosahexaenoic acid (22:6 n-3; DHA) which are the principal n-3 polyunsaturated fatty acids regarded as candidates for ...
McLennan, P.   +7 more
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Docosahexaenoic acid and arachidonic acid in infant development

Seminars in Neonatology, 2001
Docosahaxaenoic acid and arachidonic acid are highly concentrated in the central nervous system. The amount of these fatty acids in the central nervous system increases dramatically during the last intrauterine trimester and the first year of life.
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Monitoring the oxidation of docosahexaenoic acid in lipids

Lipids, 2005
AbstractThe oxidation of free DHA, DHA mixed with PC, and DHA incorporated into PC, PE, or TG was evaluated to determine which lipid provided DHA with the best protection against oxidation. DHA was either situated at the sn‐1 position, sn‐2 position, or both positions of the phospholipid, whereas the TG contained DHA at all positions.
Ann-Marie, Lyberg   +2 more
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Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle

Nutrients, 2021
Rodrigo Valenzuela   +2 more
exaly  

SOD1 Aggregation Induced by Docosahexaenoic Acid and Docosahexaenoic Acid Hydroperoxides

Free Radical Biology and Medicine, 2010
Patricia Postilione Appolinário   +3 more
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Docosahexaenoic acid

Lipidomics Gateway, 2010
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