Results 31 to 40 of about 77,870 (288)

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

Value of long-chain polyunsaturated fatty acids for infants’ health and development

Репродуктивная эндокринология, 2019
The level of intake of essential polyunsaturated fatty acids (PUFAs) in pregnant, newborns and young children affects the quality of growth, state of the cardiovascular system, neurological and immune functions in childhood and later life. Child receives
Д. О. Добрянський, Т. К. Знаменська, О. В. Воробйова, І. І. Воробйова   +3 more
doaj   +1 more source

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]

, 2017
Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella, DI RENZO, Livia Maria, Santoni, Angela, Velotti, Francesca   +3 more
core   +1 more source

Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate.

Journal of Lipid Research, 1984
Docosahexaenoic acid, an n-3 essential fatty acid, was recently shown to be enzymically converted by platelets, basophils, and liver microsomes into metabolites containing conjugated dienes with allylic hydroxyl groups. To help identify these metabolites,
M VanRollins, R C Murphy
doaj   +1 more source

Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta‐Analysis in Up to 16 126 Participants

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background We aimed at investigating the association of circulating fatty acids with coronary heart disease (CHD) and stroke risk. Methods and Results We conducted an individual‐participant data meta‐analysis of 5 UK‐based cohorts and 1 matched case ...
Maria Carolina Borges, Amand Floriaan Schmidt, Barbara Jefferis, S. Goya Wannamethee, Debbie A. Lawlor, Mika Kivimaki, Meena Kumari, Tom R. Gaunt, Yoav Ben‐Shlomo, Therese Tillin, Usha Menon, Rui Providencia, Caroline Dale, Aleksandra Gentry‐Maharaj, Alun Hughes, Nish Chaturvedi, Juan Pablo Casas, Aroon D. Hingorani   +17 more
doaj   +1 more source

Distinguishing Health Benefits of Eicosapentaenoic and Docosahexaenoic Acids

Marine Drugs, 2012
Long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) are recommended for management of patients with wide-ranging chronic diseases, including coronary heart disease, rheumatoid arthritis, dementia, and depression.
Fraser D. Russell, Corinna S. Bürgin-Maunder   +1 more
doaj   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell, Ahlberg, Balasubramaniam, Barlett, Bernd Seifferth, Berr, Berr, Berr, Berr, Carey, Carey, Carulli, Cohen, Cohen, Coleman, Dam, Delchier, Dieter Jüngst, Everson, Frieder Berr, Glenn, Goodnight, Gustav Paumgartner, Harris, Hofmann, Holan, Holzbach, Joseph Holl, Juniper, Kaludzny, Kelly, Kuroki, Leaf, Lee, Lippel, Lorenz, Magnuson, Marks, Nestel, Nestel, O'Leary, Parhofer, Paul, Phillipson, Pomeranz, Ramond, Robins, Robins, Sanders, Scobey, Sedaghat, Snedecor, Strasberg, Sven Fischer, Sömjen, Ventura, von Schacky, Wagner, Wechsler, Werner O. Richter   +59 more
core   +1 more source

Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]

, 2020
In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P, Hammock, Bruce D, Metherel, Adam H, Newman, John W, Otoki, Yurika, Pedersen, Theresa, Taha, Ameer Y, Yang, Jun   +7 more
core   +1 more source

Hydrophobic Ligand Binding by Zn-α_2-glycoprotein, a Soluble Fat-depleting Factor Related to Major Histocompatibility Complex Proteins [PDF]

, 2001
Zn-alpha2-glycoprotein (ZAG) is a member of the major histocompatibility complex (MHC) class I family of proteins and is identical in amino acid sequence to a tumor-derived lipid-mobilizing factor associated with cachexia in cancer patients.
Bjorkman, Pamela J., Cooper, Alan, Heikema, Astrid P., Kennedy, Malcolm W., Sánchez, Luis M.   +4 more
core   +1 more source

Phase Equilibrium and Optimization Tools: Application for Enhanced Structured Lipids for Foods [PDF]

, 2011
Solid-liquid phase equilibrium modeling of triacylglycerols mixtures is essential for lipids design. Considering the α polymorphism and liquid phase as ideal, the Margules 2-suffix excess Gibbs energy model with predictive binary parameter correlations ...
Carrillo Le Roux, Galo, Gerbaud, Vincent, Teles dos Santos, Moises   +2 more
core   +2 more sources