Results 41 to 50 of about 1,082,320 (275)

Omega 3 fatty acids and cognitive health in older people. [PDF]

, 2012
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have been proposed as protective against dementia and age related cognitive impairment.
Dangour, Alan, Uauy, Ricardo, Dangour, Alan D, Andreeva, Valentina, Andreeva, Valentina A, Sydenham, Emma   +5 more
core   +1 more source

Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation

Journal of Lipid Research, 1998
The 3-thia fatty acids, tetradecylthioacetic acid and 3,10-dithiadicarboxylic acid are mitochondrion and peroxisome proliferators. Administration of these promotes an increased transport of endogenous fatty acids to these organelles and a higher capacity
Lise Madsen, Livar Frøyland, Endre Dyrøy, Kari Helland, Rolf K. Berge   +4 more
doaj   +1 more source

Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation [PDF]

Frontiers in Pharmacology, 2019
Cystic fibrosis (CF) is an autosomal recessive disorder, caused by genetic mutations in CF transmembrane conductance regulator protein. Several reports have indicated the presence of specific fatty acid alterations in CF patients, most notably decreased levels of plasmatic and tissue docosahexaenoic acid (DHA), the precursor of specialized pro ...
Elisabetta Teopompi, Patrizia Risé, Roberta Pisi, Carola Buccellati, Marina Aiello, Giovanna Pisi, Candida Tripodi, Valentina Fainardi, Enrico Clini, Enrico Clini, Alfredo Chetta, G. Enrico Rovati, Angelo Sala, Angelo Sala   +13 more
openaire   +6 more sources

Exploring the Role of Polyunsaturated Fatty Acids in Children’s Sleep

Biomedicines
Research on the effects of polyunsaturated fatty acids on children’s sleep has made significant advancements. This study explores the unique pathways through which polyunsaturated fatty acids, particularly docosahexaenoic acid and eicosapentaenoic acid ...
Liuyan Zhu, Bingquan Zhu, Dan Yao
doaj   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta‐Analysis in Up to 16 126 Participants

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background We aimed at investigating the association of circulating fatty acids with coronary heart disease (CHD) and stroke risk. Methods and Results We conducted an individual‐participant data meta‐analysis of 5 UK‐based cohorts and 1 matched case ...
Maria Carolina Borges, Amand Floriaan Schmidt, Barbara Jefferis, S. Goya Wannamethee, Debbie A. Lawlor, Mika Kivimaki, Meena Kumari, Tom R. Gaunt, Yoav Ben‐Shlomo, Therese Tillin, Usha Menon, Rui Providencia, Caroline Dale, Aleksandra Gentry‐Maharaj, Alun Hughes, Nish Chaturvedi, Juan Pablo Casas, Aroon D. Hingorani   +17 more
doaj   +1 more source

The g.4290 C>G Polymorphism in the FADS2 Gene Modifies the Fatty Acid Profile of the Pectoralis Superficialis Muscle of Ross 308 Broiler Chickens

Animals, 2022
The effect of the g.4290 C>G substitution in the FADS2 gene and g.285 C>T in the FABP4 gene on carcass quality, meat quality, and fatty acid profile of the pectoralis superficialis muscle of 238 male broiler chickens reared up to 45 days of age was ...
Urszula Kaczor, Sebastian Sawicki, Joanna Nowak, Julia Gabryś, Jakub Jurczyk, Dorota Wojtysiak, Katarzyna Połtowicz   +6 more
doaj   +1 more source

Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity

Advanced Science, EarlyView.
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou, Siyu Li, Chunying Li, Zhifan Lin, Dan He, Li Yang, Liping Fu, Qianyue Zhang, Tianping Zhou, Yao Yao, Xiaolei Yin   +10 more
wiley   +1 more source

Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells [PDF]

Asian-Australasian Journal of Animal Sciences, 2016
Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis.
Zhixin Guo, Yanfeng Wang, Xue Feng, Chaogetu Bao, Qiburi He, Lili Bao, Huifang Hao, Zhigang Wang   +7 more
doaj   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source