Results 61 to 70 of about 1,082,320 (275)

Pretranslational regulation of cytochrome P4504A1 by free fatty acids in primary cultures of rat hepatocytes.

open access: yesJournal of Lipid Research, 1994
The effect of different fatty acids on cytochrome P4504A1 mRNA levels was studied in primary cultures of rat hepatocytes, using a solution hybridization assay. All fatty acids tested induced P4504A1 mRNA levels in a dose- and time-dependent manner.
P Tollet   +4 more
doaj   +1 more source

HEALTH BENEFITS OF DOCOSAHEXAENOIC ACID (DHA) [PDF]

open access: yesPharmacological Research, 1999
Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in learning.
L A, Horrocks, Y K, Yeo
openaire   +2 more sources

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini   +2 more
wiley   +1 more source

A randomised controlled trial investigating the effect of n-3 long-chain polyunsaturated fatty acid supplementation on cognitive and retinal function in cognitively healthy older people: the Older People And n-3 Long-chain polyunsaturated fatty acids (OPAL) study protocol [ISRCTN72331636]. [PDF]

open access: yes, 2006
The number of individuals with age-related cognitive impairment is rising dramatically in the UK and globally. There is considerable interest in the general hypothesis that improving the diet of older people may slow the progression of cognitive decline.
Hardy, Pollyanna   +55 more
core   +4 more sources

Unique lipids of primate spermatozoa: desmosterol and docosahexaenoic acid.

open access: yesJournal of Lipid Research, 1993
Spermatozoa represent a tissue readily accessible for study after various exogenous perturbations. To characterize the lipid composition of monkey sperm and to establish a baseline from which dietary or pharmaceutical influences may then be evaluated, we
DS Lin   +4 more
doaj   +1 more source

Precision Fermentation for Next Generation Food Ingredients: Technological Foundations, Food Applications, Sustainability, and Regulatory Challenges

open access: yesFood Bioengineering, EarlyView.
Precision fermentation uses engineered microorganisms to produce targeted food ingredients, including proteins, enzymes, lipids, flavors, vitamins, and bioactives. This review examines its technological foundations, food applications, safety, sustainability, economics, regulation, and consumer acceptance, emphasizing that performance depends on host ...
Nora Ali Hassan   +2 more
wiley   +1 more source

Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA) [PDF]

open access: yes, 2007
Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues ...
Hans Demmelmair   +5 more
core   +2 more sources

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

open access: yesFood Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang   +8 more
wiley   +1 more source

Omega-3 Index and Sudden Cardiac Death [PDF]

open access: yes, 2010
Sudden cardiac death (SCD) is an unresolved health issue, and responsible for 15% of all deaths in Western countries. Epidemiologic evidence, as well as evidence from clinical trials, indicates that increasing intake and high levels of eicosapentaenoic ...
Schacky, Clemens von, Von Schacky
core   +1 more source

Docosahexaenoic Acid and Cognition throughout the Lifespan [PDF]

open access: yesNutrients, 2016
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid (PUFA) found in the brain and can affect neurological function by modulating signal transduction pathways, neurotransmission, neurogenesis, myelination, membrane receptor function, synaptic plasticity, neuroinflammation, membrane integrity and membrane organization ...
Weiser, Michael J.   +2 more
openaire   +2 more sources

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