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Docosahexaenoic acid (DHA) is a long-chain, highly unsaturated omega-3 (n-3) fatty acid. It has a structure that gives it unique physical and functional properties. DHA is metabolically related to other n-3 fatty acids: it can be synthesised from the plant essential fatty acid α-linolenic acid (ALA).
Caroline, Richard, Philip C, Calder
+12 more sources
The effects of parenteral or dietary omega-3 polyunsaturated fatty acids in rat models of spinal cord injury [PDF]
PhDThere is currently no effective treatment for spinal cord injury (SCI). Long chain omega-3 polyunsaturated fatty acids (PUFA) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have beneficial effects in various neurological disorders.
Hall, Jodie Christine Elizabeth
core +4 more sources
Docosahexaenoic acid neurolipidomics [PDF]
Mediator lipidomics is a field of study concerned with the characterization, structural elucidation and bioactivity of lipid derivatives actively generated by enzymatic activity. It is well known that omega-3 fatty acids are beneficial for brain function.
Tiffany D, Niemoller, Nicolas G, Bazan
openaire +2 more sources
The essentiality of arachidonic acid and docosahexaenoic acid [PDF]
The purpose of this review is to correlate the clinical finding that patients receiving parenteral nutrition with a fish oil-based lipid emulsion do not develop essential fatty acid deficiency (EFAD) with an experimental murine model, thus showing that arachidonic acid (AA) and docosahexaenoic acid (DHA) are likely to be the essential fatty acids ...
Hau D, Le +4 more
openaire +2 more sources
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood [PDF]
Objective: To investigate the relation between breastfeeding, use of docosahexaenoic acid (DHA)-fortified formula and neuropsychological function in children. Design Prospective cohort study. Setting Southampton, UK.
West, Carolyn +36 more
core +1 more source
In order to understand the mechanisms by which fatty acids are taken up by the placenta, the uptake of oleic, linoleic, arachidonic, and docosahexaenoic acids by cultured human placental choriocarcinoma (BeWo) cells was examined.
F M Campbell +4 more
doaj +1 more source
Docosahexaenoic Acid and Preterm Birth [PDF]
Preterm birth accounts for more than 85% of all perinatal complications and deaths. There are many short- and long-term consequences of being born too soon. These infants often require intensive care and are at increased risk of early morbidities often with life-long sequelae.
Makrides, M., Best, K.
openaire +3 more sources
Omega 3 fatty acids on child growth, visual acuity and neurodevelopment. [PDF]
The aim of this review is to evaluate the effects of omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) supplementation in pregnant and lactating women and infants during postnatal life, on the visual acuity, psychomotor development, mental ...
Anjos, Tania +8 more
core +1 more source
Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat
Dietary triglycerides containing predominantly poly-unsaturated fatty acids (PUFAs) are known to reduce plasma total and low density lipoprotein (LDL) cholesterol concentrations relative to triglycerides containing predominantly saturated fatty acids ...
DK Spady
doaj +1 more source

