Results 41 to 50 of about 178,781 (301)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Paradoxes of Doctoral Studies in Education Sciences in the Czech Republic

Qualitative Sociology Review, 2021
Adequate staffing of university studies with qualified academics was completed thanks to the reimplementation of three-stage university education during the post-socialist restoration of higher education in the Czech Republic.
Miroslav Dopita, Jana Poláchová Vašťatková   +1 more
doaj   +1 more source

Initial teacher education and the New Zealand curriculum.

, 2010
New Zealand teacher educators are faced with the challenge of how to prepare their student teachers to become beginning teachers who are able to base their teaching upon the national curriculum.
Cooper, Beverley, Cowie, Bronwen, McGee, Clive   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Doctoral Studies in the Context of Global Trends: Problems and Key Factors of Development

Высшее образование в России, 2022
The article focuses on the analysis of the current state, problems and key factors in the development of Russian doctoral education in connection with its transition from 2022/2023 academic year to the implementation of a new model in the context of ...
M. V. Seroshtan, K. A. Artamonova, G. Z. Akimova, E. V. Berezhnaya, E. V. Seroshtan   +4 more
doaj   +1 more source

Time mapping : charting transcultural and First Nations histories and geographies in doctoral education

, 2021
In this article, we introduce a time mapping methodology to chart the impact of transcultural and First Nations’ histories, geographies and cultural knowledges on doctoral education.
Manathunga, Catherine, Bunda, Tracey, Singh, Michael (R10515), Qi, Jing   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Doctoral carers : tracing contradictory discourses and identifying possibilities for a more care-full doctoral education

, 2022
Drawing on data from an empirical study in Aotearoa New Zealand, our chapter contributes to the theorisation of care and carers in doctoral education. We closely analyse two self-portraits and related diary-interview data produced by a doctoral parent ...
Mitchell, Cat, Burford, James
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Factors associated with the permanence of doctoral students. A scoping review

Frontiers in Psychology
The permanence of students in doctoral programs is a multi-causal phenomenon, which makes it difficult to address and leads to an isolated investigation of its causes, being necessary a joint understanding.
Edna Hurtado, Edna Hurtado, Esther Rosado, Martin Aoiz, Soledad Quero, Soledad Quero, Elkin O. Luis   +6 more
doaj   +1 more source