Results 91 to 100 of about 33,626 (230)

Quality of Medicare Skilled Home Health for People Living With Dementia in the US: National Patterns and Implications

Journal of the American Geriatrics Society, EarlyView.
There is wide variation in receipt of care from a high‐quality home health agency for people with dementia across the United States. ABSTRACT Background People living with dementia frequently use Medicare skilled home health care and have unique usage patterns as compared to people without dementia, but little is known about variation in measured ...
Jennifer M. Reckrey, Bian Liu, Arushi Arora, Christine Ritchie, Bruce Leff, Abraham A. Brody, Julia G. Burgdorf, Katherine A. Ornstein   +7 more
wiley   +1 more source

Bayesian Value-of-Information Analysis: An Application to a Policy Model of Alzheimer's Disease [PDF]

A framework is presented which distinguishes the conceptually separate decisions of which treatment strategy is optimal from the question of whether more information is required to inform this choice in the future.
K. Claxton, M. C. Weinstein, P. J. Neumannn, S. S. Araki   +3 more
core  

Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology [PDF]

, 2017
The British Association for Psychopharmacology coordinated a meeting of experts to review and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As before, levels of evidence were rated using accepted standards which were
Burns, A, Holmes, C, Jones, M, Jones, R, Livingston, G, McKeith, I, Mittler, P, O'Brien, JT, Passmore, P, Ritchie, C, Robinson, L, Sampson, EL, Taylor, J-P, Thomas, A   +13 more
core   +2 more sources

Characteristics of the Long‐Term Care Data Cooperative: A New Resource for Research on Outcomes in Long‐Term Care

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The long‐term care (LTC) Data Cooperative is a National Institute on Aging‐funded data resource that links skilled nursing facility (SNF) electronic health record (EHR) data with Medicare and Medicaid claims for use in comparative effectiveness and interventional research.
Stephanie M. Kissam, Terry Hawk, Amy Recker, Catherine Rogers Murray, Dustin Burns, David D. Dore, David R. Gifford, Vincent Mor, Elizabeth M. White   +8 more
wiley   +1 more source

Clinical Observation on Basal Ganglia Aphasia after Stroke Treated by Donepezil

康复学报, 2015
Objective:To evaluate the curative effect of donepezil on basal ganglia aphasia after stroke.Methods:A total of 37 patients with basal ganglia aphasia after stroke were randomly assigned to donepezil group (n=19) and control group (n=18).
Xi CHENG, Jinghui LAI, Zhifeng WANG, Yanling GAO, Xiaofeng CHEN, Ling LIN   +5 more
doaj  

Association Between Cholinesterase Inhibitor‐Overactive Bladder Antimuscarinic Prescribing Cascade and Risk of Delirium and Falls Among Individuals Living With Dementia

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Prescribing cascades occur when cholinesterase inhibitor (ChEI)‐induced urinary incontinence is misinterpreted as a new condition, leading to overactive bladder (OAB) antimuscarinic initiation. We evaluated whether the ChEI‐OAB antimuscarinic prescribing cascade was associated with delirium or falls compared with mirabegron in older
Sarah Beth Tucker, Bryan L. Love, Chijioke M. Okeke, Erin D. Zwick, Chengwen Teng, Jingkai Wei, Ibraheem M. Karaye, Saud Alsahali, Krithika Rajagopalan, Ismaeel Yunusa   +9 more
wiley   +1 more source

Donepezil Combined with Natural Hirudin Improves the Clinical Symptoms of Patients with Mild-to-Moderate Alzheimer's Disease: A 20-Week Open-Label Pilot Study

International Journal of Medical Sciences, 2012
Aim: To evaluate the efficacy and safety of donepezil plus natural hirudin in patients with mild-to-moderate Alzheimer's Disease. Methods: In the 20-week, randomized, open-label and controlled study, 84 patients received either donepezil (5 mg/day for ...
De-qiang Li, Yu-ping Zhou, Han Yang
doaj  

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Validity, Significance, Strengths, Limitations, and Evidentiary Value of Real-World Clinical Data for Combination Therapy in Alzheimer's Disease: Comparison of Efficacy and Effectiveness Studies [PDF]

, 2014
Background: Randomized controlled efficacy trials (RCTs), the scientific gold standard, are required for regulatory approval of Alzheimer's disease (AD) interventions, yet provide limited information regarding real-world therapeutic effectiveness ...
Atri, Alireza, Doody, Rachelle S., Lopez, Oscar L., Rountree, Susan D.   +3 more
core   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source