Results 181 to 190 of about 21,434 (231)
<i>Schisandra chinensis</i> Pomace Attenuates Scopolamine-Induced Cholinergic Dysfunction Associated with Changes in BDNF and JNK Signaling. [PDF]
Curr Issues Mol BiolYoon JH +10 more
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Cholinesterase inhibitors for patients with dementia: Patterns of prescribing and disparities in treatment. [PDF]
J Alzheimers DisHeo RJ +8 more
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Prescription cascades associated with acetylcholinesterase inhibitors use: a high-throughput sequence symmetry analysis. [PDF]
Age AgeingNewby D +14 more
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Modulation of experimental Alzheimer's disease in rats through donepezil-loaded CSF implant. [PDF]
Sci RepOsama L +4 more
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Modulation of programmed cell death by botanical drugs in Alzheimer's disease: a review from a traditional Chinese medicine perspective. [PDF]
Front PharmacolLi B, Cui Z, Xu Y, Xu M.
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Expert Opinion on Pharmacotherapy, 2007
Donepezil hydrochloride is the most widely prescribed drug for Alzheimer's disease (AD). The main mechanism of action through which it influences cognition and function is presumed to be the inhibition of acetylcholinesterase enzyme in the brain; however, donepezil may also impact the pathophysiology of AD at several other points.
Ben Seltzer
exaly +3 more sources
Donepezil hydrochloride is the most widely prescribed drug for Alzheimer's disease (AD). The main mechanism of action through which it influences cognition and function is presumed to be the inhibition of acetylcholinesterase enzyme in the brain; however, donepezil may also impact the pathophysiology of AD at several other points.
Ben Seltzer
exaly +3 more sources
Drugs & Aging, 1997
Donepezil is a specific and potent acetylcholinesterase inhibitor according to in vitro data. It displays primarily noncompetitive inhibitory activity. In vivo, donepezil inhibited acetylcholinesterase activity in human erythrocytes and increased extracellular acetylcholine levels in the cerebral cortex and hippocampus of the rat.
H M, Bryson, P, Benfield
openaire +3 more sources
Donepezil is a specific and potent acetylcholinesterase inhibitor according to in vitro data. It displays primarily noncompetitive inhibitory activity. In vivo, donepezil inhibited acetylcholinesterase activity in human erythrocytes and increased extracellular acetylcholine levels in the cerebral cortex and hippocampus of the rat.
H M, Bryson, P, Benfield
openaire +3 more sources
Drugs & Aging, 2003
Vascular dementia (VaD), caused by stroke or small vessel disease, is the second most common form of dementia after Alzheimer's disease (AD). Donepezil, an acetylcholinesterase inhibitor currently indicated for use in patients with mild to moderate AD, has recently been evaluated in VaD.
David R, Goldsmith, Lesley J, Scott
openaire +2 more sources
Vascular dementia (VaD), caused by stroke or small vessel disease, is the second most common form of dementia after Alzheimer's disease (AD). Donepezil, an acetylcholinesterase inhibitor currently indicated for use in patients with mild to moderate AD, has recently been evaluated in VaD.
David R, Goldsmith, Lesley J, Scott
openaire +2 more sources