Results 141 to 150 of about 122,423 (305)

Notch signaling modulates the survival of dopaminergic neurons.

open access: yes, 2015
(A) Survivability of dopaminergic neurons is improved by Dl inhibition (** p < 0.01, * p < 0.05 vs. White RNAi; # p < 0.01, † p < 0.05 vs. LacZ RNAi by one-way ANOVA.
Hongrui Meng (636865)   +16 more
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Dopaminergic neurons require synaptic vesicle recycling for sustained flight.

open access: yes, 2018
(A) Acute expression of a temperature sensitive dynamin mutant (Shits) in adult dopaminergic neurons reduced flight bout durations when tested at 30°C as compared to a control tested at 22°C (THD1>Shits at 22°C compared to 30°C; n≥30, **pTHD1/+ and Shits/
Gaiti Hasan (208080)   +2 more
core   +1 more source

Ablation of NAMPT in dopaminergic neurons leads to neurodegeneration and induces Parkinson’s disease in mouse

open access: yesBrain Research Bulletin
Nicotinamide phosphoribosyltransferase (NAMPT) is the key enzyme in the salvaging synthesize pathway of nicotinamide adenine dinucleotide (NAD). The neuroprotective roles of NAMPT on neurodegeneration have been explored in aging brain and Alzheimer’s ...
Cong Chen   +5 more
doaj   +1 more source

Models of midbrain dopaminergic neurons

open access: yesScholarpedia, 2007
Alexey S. Kuznetsov   +3 more
openaire   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development

open access: yes, 2014
International audienceDopaminergic neurons of the substantia nigra pars compacta (SNc) are involved in the control of movement, sleep, reward, learning, and nervous system disorders and disease.
Adele Woodhouse   +5 more
core   +1 more source

Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Hyperactivity is a persistent and clinically relevant symptom in anorexia nervosa (AN). Hyperactivity is inversely correlated with leptin levels. While systemic leptin administration attenuates hyperactivity in rodent models, the specific brain regions mediating this effect remain unclear.
Nick J. M. Papavoine   +6 more
wiley   +1 more source

Ultra‐Processed Food Intake and its Association With Eating Disorders: A Scoping Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Ultra‐processed foods have been associated with adverse health outcomes, but their relationship with eating disorders remains unclear. This scoping review mapped the available evidence on the association between ultra‐processed food intake and eating disorders in adolescents and adults.
Marthina Streda Walker   +4 more
wiley   +1 more source

Decreased NAD+ in dopaminergic neurons

open access: yesAging, 2018
Sison, Samantha L., Ebert, Allison D.
openaire   +2 more sources

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