Results 31 to 40 of about 72,919 (193)

Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage [PDF]

, 2017
Sex chromosomes differentiated from different ancestral autosomes in various vertebrate lineages. Here, we trace the functional evolution of the XY Chromosomes of the green anole lizard (Anolis carolinensis), on the basis of extensive high-throughput ...
Brüning, T, Conrad, C, Cortez, D, Halbert, J, Julien, P, Kaessmann, H, Kerver, HN, Lamanna, F, Leushkin, E, Liechti, A, Marin, R, Mössinger, K, Pradeepa, MM, Trefzer, T, Tschopp, P, Wade, J   +15 more
core   +3 more sources

Masc‐induced dosage compensation in silkworm cultured cells

FEBS Open Bio, 2019
The Masculinizer (Masc) gene encodes a CCCH‐tandem zinc finger protein that controls both masculinization and dosage compensation in the silkworm Bombyx mori.
Susumu Katsuma, Keisuke Shoji, Yudai Sugano, Yutaka Suzuki, Takashi Kiuchi   +4 more
doaj   +1 more source

Condensin-mediated chromosome organization and gene regulation

Frontiers in Genetics, 2015
In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene regulatory mechanism called dosage compensation equalizes X-linked gene expression between the ...
Alyssa Christine Lau, Gyorgyi eCsankovszki   +1 more
doaj   +1 more source

Sex Chromosome Dosage Compensation in Heliconius Butterflies: Global yet Still Incomplete? [PDF]

, 2015
The evolution of heterogametic sex chromosomes is often-but not always-accompanied by the evolution of dosage compensating mechanisms that mitigate the impact of sex-specific gene dosage on levels of gene expression.
Hardcastle, Thomas J, Jiggins, Chris D, Walters, James R   +2 more
core   +3 more sources

A General Mechanism for Network-Dosage Compensation in Gene Circuits [PDF]

, 2010
Coping with variations in network dosage is crucial for maintaining optimal function in gene networks. We explored how network structure facilitates network-level dosage compensation.
Acar, Murat, Arnold, Frances H., Elowitz, Michael B., Pando, Bernardo F., van Oudenaarden, Alexander   +4 more
core   +2 more sources

Large-scale population study of human cell lines indicates that dosage compensation is virtually complete. [PDF]

PLoS Genetics, 2008
X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing.
Colette M Johnston, Frances L Lovell, Daniel A Leongamornlert, Barbara E Stranger, Emmanouil T Dermitzakis, Mark T Ross   +5 more
doaj   +1 more source

Progress and prospects toward our understanding of the evolution of dosage compensation [PDF]

, 2009
In many eukaryotic organisms, gender is determined by a pair of heteromorphic sex chromosomes. Degeneration of the non-recombining Y chromosome is a general facet of sex chromosome evolution.
A Eisen, A Hilfiker, AA Alekseyenko, AD Cutter, AG Cock, AP Arnold, AY Albert, B Charlesworth, B Charlesworth, B Lemos, B Payer, B Vicoso, Beatriz Vicoso, BJ Meyer, BT Lahn, C Chureau, CJ Tsai, D Bachtrog, D Bachtrog, D Bachtrog, D Bachtrog, D Bachtrog, D Bachtrog, D Charlesworth, D Fagegaltier, D Guttman, DJ Begun, DK Nguyen, DL Lindsley, Doris Bachtrog, E Larschan, EA Elisaphenko, ER Smith, F Li, G Bashaw, G Hendriks, H Ellegren, H Ellegren, H Ellegren, H Lin, HE Dawes, HK Reeve, HS Chandra, J Engelstädter, J Engelstädter, J Jans, J Kind, J Larsson, J Larsson, JAM Graves, JB Drost, JD Lieb, JD Lieb, JJ Bull, JS Mattick, KA Hagstrom, KA Hagstrom, L Carrel, L Duret, LV Matyunina, M Lyon, M Vitkova, MA Rodriguez, MF Lyon, MF Ruiz, MS Johnson, P Haddrill, P McDonel, PR Baverstock, PT Chuang, R. L. Kelley, S Berlin, S Berlin, S Inagaki, S Zhou, S-W Park, T Hirano, T Miyata, T Straub, TH Sural, V. Gupta, WG Hill, WM White, WR Rice, WR Rice, X Zha, Y Itoh, Y Kageyama, Y Park, Z Liu   +89 more
core   +3 more sources

Absence of X-chromosome dosage compensation in the primordial germ cells of Drosophila embryos

Scientific Reports, 2021
Dosage compensation is a mechanism that equalizes sex chromosome gene expression between the sexes. In Drosophila, individuals with two X chromosomes (XX) become female, whereas males have one X chromosome (XY).
Ryoma Ota, Makoto Hayashi, Shumpei Morita, Hiroki Miura, Satoru Kobayashi   +4 more
doaj   +1 more source

The C. elegans dosage compensation complex mediates interphase X chromosome compaction [PDF]

, 2014
Background Dosage compensation is a specialized gene regulatory mechanism which equalizes X-linked gene expression between sexes. In Caenorhabditis elegans, dosage compensation is achieved by the activity of the dosage compensation ...
Csankovszki, Györgyi, Lau, Alyssa C, Nabeshima, Kentaro   +2 more
core   +1 more source

Massive gene amplification on a recently formed Drosophila Y chromosome. [PDF]

, 2019
Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
Bachtrog, Doris, Bracewell, Ryan, Mahajan, Shivani   +2 more
core   +1 more source