Epigenetics & Chromatin, 2018 Background In animals with XY sex chromosomes, X-linked genes from a single X chromosome in males are imbalanced relative to autosomal genes. To minimize the impact of genic imbalance in male Drosophila, there is a dosage compensation complex (MSL) that ...
Hangnoh Lee, Brian Oliver
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Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation. [PDF]
PLoS Genetics, 2016 Dosage compensation is an essential process that equalizes transcript levels of X-linked genes between sexes by forming a domain of coordinated gene expression.
Guray Kuzu +14 more
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Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage [PDF]
, 2017 Sex chromosomes differentiated from different ancestral autosomes in various vertebrate lineages. Here, we trace the functional evolution of the XY Chromosomes of the green anole lizard (Anolis carolinensis), on the basis of extensive high-throughput ...
Brüning, T +15 more
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Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome. [PDF]
, 2016 In many diploid species, sex determination is linked to a pair of sex chromosomes that evolved from a pair of autosomes. In these organisms, the degeneration of the sex-limited Y or W chromosome causes a reduction in gene dose in the heterogametic sex ...
Dessimoz, C. +3 more
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X-to-autosome expression and msl-2 transcript abundance correlate among Drosophila melanogaster somatic tissues [PDF]
PeerJ, 2015 In Drosophila melanogaster, the male-specific lethal (MSL) complex has been studied extensively for its role in upregulating male X-linked genes. Recent advances in high-throughput technologies have improved our understanding of how the MSL complex ...
Steven P. Vensko II, Eric A. Stone
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Dosage compensation: X-repress yourself [PDF]
, 1997 Dosage compensation in Caenorhabditis elegans involves the sex-specific recruitment to the X chromosome of a protein complex, the nature of which suggests that there are mechanistic links between chromosome segregation and global transcriptional ...
Riggs +16 more
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PLoS Genetics, 2021 Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensation
Evan Witt +4 more
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Sex Chromosome Dosage Compensation in Heliconius Butterflies: Global yet Still Incomplete? [PDF]
, 2015 The evolution of heterogametic sex chromosomes is often-but not always-accompanied by the evolution of dosage compensating mechanisms that mitigate the impact of sex-specific gene dosage on levels of gene expression.
Hardcastle, Thomas J +2 more
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Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae [PDF]
, 2020 Pyflubumide is a novel selective carboxanilide acaricide that inhibits mitochondrial complex II of spider mite species such as Tetranychus urticae. We explored the baseline toxicity and potential cross-resistance risk of pyflubumide in a reference panel ...
Fotoukkiaii, Seyedeh Masoumeh +3 more
core +1 more source
Condensin-mediated chromosome organization and gene regulation
Frontiers in Genetics, 2015 In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene regulatory mechanism called dosage compensation equalizes X-linked gene expression between the ...
Alyssa Christine Lau +1 more
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