Results 51 to 60 of about 663,689 (174)
Study of Dosage Compensation in Drosophila
Abstract Using a sensitive RT-QPCR assay, we analyzed the regulatory effects of sex and different dosage compensation mutations in Drosophila. To validate the assay, we showed that regulation for several genes indeed varied with the number of functional copies of that gene.
Pei-Wen, Chiang, David M, Kurnit
openaire +2 more sources
Global analysis of X-chromosome dosage compensation
Background Drosophila melanogaster females have two X chromosomes and two autosome sets (XX;AA), while males have a single X chromosome and two autosome sets (X;AA).
Malley James D +8 more
doaj +1 more source
Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levels. [PDF]
Dosage compensation is a specialized form of gene regulation that balances sex-chromosome linked gene expression between the sexes. In C. elegans, dosage compensation is achieved by the activity of the dosage compensation complex (DCC).
Emily Petty +2 more
doaj +1 more source
2010, 1st quarter-; Description based on: 1st quarter 2010; title from PDF caption (viewed on Dec. 7, 2010).; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board."; Harvested from the web on 12/9 ...
core +4 more sources
Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated ...
Koji Ishikawa +2 more
doaj +1 more source
Global chromatin conformation differences in the Drosophila dosage compensated chromosome X
In Drosophila, dosage compensation involves a twofold transcriptional upregulation of the single male chromosome X. Here the authors show that global conformational differences are specifically present in the male X chromosome and detectable using Hi-C ...
Koustav Pal +9 more
doaj +1 more source
Dosage compensation is less effective in birds than in mammals
Background In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical for species survival. Diverse molecular mechanisms have evolved to effectively balance the expressed dose of X-linked genes ...
Itoh Yuichiro +12 more
doaj +1 more source
Compensation Review Board (CRB) opinions. 2005
Updated annually; Began in 2003?; Title from home page last rev. Feb. 6, 2007 (publisher's web site, viewed Mar.
Connecticut. Workers' Compensation Commission. Compensation Review Board.
core +1 more source
Compensation Review Board (CRB) opinions. 2006
Updated annually; Began in 2003?; Title from home page last rev. Feb. 6, 2007 (publisher's web site, viewed Mar.
Connecticut. Workers' Compensation Commission. Compensation Review Board.
core +1 more source
Chromosome-specific regulatory mechanisms provide a model to understand the coordinated regulation of genes on entire chromosomes or on larger genomic regions. In fruit flies, two chromosome-wide systems have been characterized: The male-specific lethal (
Samaneh Ekhteraei-Tousi +2 more
doaj +1 more source

