Results 31 to 40 of about 1,171,051 (326)

femaleless Controls Sex Determination and Dosage Compensation Pathways in Females of Anopheles Mosquitoes

Current Biology, 2021
Summary The insect sex determination and the intimately linked dosage compensation pathways represent a challenging evolutionary puzzle that has been solved only in Drosophila melanogaster.
E. Krzywinska, L. Ferretti, Jianwei Li, Jian-Chiuan Li, Chun-Hong Chen, J. Krzywinski   +5 more
semanticscholar   +1 more source

Dosage compensation in birds [PDF]

Current Biology, 2001
The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ). Therefore male birds, like female mammals, carry a double dose of sex-linked genes relative to the other sex.
McQueen, H A, McBride, D, Miele, G, Bird, A P, Clinton, M   +4 more
openaire   +3 more sources

Dosage compensation in Bombyx mori is achieved by partial repression of both Z chromosomes in males

bioRxiv, 2021
Interphase chromatin is organized precisely to facilitate accurate gene expression. The structure-function relationship of chromatin is epitomized in sex chromosome dosage compensation (DC), where sex-linked gene expression is balanced between males and ...
Leah F. Rosin, Yang Chen, E. Lei
semanticscholar   +1 more source

A male-essential miRNA is key for avian sex chromosome dosage compensation. [PDF]

Nature
Fallahshahroudi A, Yousefi Taemeh S, Rodríguez-Montes L, Trost N, Frank D, Lafrenz P, Koubek J, Tellez G, Ballantyne M, Idoko-Akoh A, Taylor L, Sherman A, Davey M, Ma C, Sorato E, Johnsson M, Grozou C, Xue Y, Liu L, Kramer G, Rubin CJ, Cardoso-Moreira M, McGrew MJ, Kaessmann H.   +23 more
europepmc   +2 more sources

Genome assembly, sex-biased gene expression and dosage compensation in the damselfly Ischnura elegans.

Genomics, 2021
The evolution of sex chromosomes, and patterns of sex-biased gene expression and dosage compensation, are poorly known among early winged insects such as odonates.
P. Chauhan, Janne Swaegers, R. S. Guillén, E. Svensson, M. Wellenreuther, B. Hansson   +5 more
semanticscholar   +1 more source

Dosage Compensation in Mammals [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor Y. The imbalance in expression of several hundred genes is lethal if not dealt with by dosage compensation.
Neil, Brockdorff, Bryan M, Turner
openaire   +2 more sources

Partial dosage compensation in Strepsiptera, a sister group of beetles. [PDF]

, 2015
Sex chromosomes have evolved independently in many different taxa, and so have mechanisms to compensate for expression differences on sex chromosomes in males and females. Different clades have evolved vastly different ways to achieve dosage compensation,
Bachtrog, Doris, Mahajan, Shivani
core   +2 more sources

Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes. [PDF]

PLoS Genetics, 2017
Understanding buffering mechanisms for various perturbations is essential for understanding robustness in cellular systems. Protein-level dosage compensation, which arises when changes in gene copy number do not translate linearly into protein level, is ...
Koji Ishikawa, Koji Makanae, Shintaro Iwasaki, Nicholas T Ingolia, Hisao Moriya   +4 more
doaj   +1 more source

Rapid Evolution of Autosomal Binding Sites of the Dosage Compensation Complex in Drosophila melanogaster and Its Association With Transcription Divergence

Frontiers in Genetics, 2021
How pleiotropy influences evolution of protein sequence remains unclear. The male-specific lethal (MSL) complex in Drosophila mediates dosage compensation by 2-fold upregulation of the X chromosome in males.
Aimei Dai, Yushuai Wang, Anthony Greenberg, Zhongqi Liufu, Tian Tang   +4 more
doaj   +1 more source

Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome. [PDF]

, 2016
In many diploid species, sex determination is linked to a pair of sex chromosomes that evolved from a pair of autosomes. In these organisms, the degeneration of the sex-limited Y or W chromosome causes a reduction in gene dose in the heterogametic sex ...
Dessimoz, C., Harrison, P.W., Mank, J.E., Zimmer, F.   +3 more
core   +2 more sources