Results 11 to 20 of about 663,689 (174)
Dosage compensation in birds [PDF]
Current Biology, 2001 The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ).
Bird, Adrian P +14 more
core +5 more sources
A Synthetic Sponge System Against miRNAs of the miR-17/92 Cluster Targets Transcriptional MYC Dosage Compensation in Aneuploid Cancer [PDF]
CellsBackground: Genomic instability, a hallmark of cancer, leads to copy number variations disrupting gene dosage balance and contributing to tumor progression.
Diana M. Bravo-Estupiñan +9 more
doaj +2 more sources
, 2010 2010, 1st quarter-; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board.
core +16 more sources
The sex-specific factor SOA controls dosage compensation in Anopheles mosquitoes [PDF]
Nature, 2023 Frank Rühle +2 more
exaly +2 more sources
When Down Is Up: Heterochromatin, Nuclear Organization and X Upregulation
Cells, 2021 Organisms with highly differentiated sex chromosomes face an imbalance in X-linked gene dosage. Male Drosophila solve this problem by increasing expression from virtually every gene on their single X chromosome, a process known as dosage compensation ...
Reem Makki, Victoria H. Meller
doaj +1 more source
Dosage Compensation in Mammals [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor Y. The imbalance in expression of several hundred genes is lethal if not dealt with by dosage compensation.
Neil, Brockdorff, Bryan M, Turner
openaire +2 more sources
Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1. [PDF]
PLoS Genetics, 2009 Dosage compensation ensures similar levels of X-linked gene products in males (XY or XO) and females (XX), despite their different numbers of X chromosomes.
Emily L Petty +4 more
doaj +1 more source
Sex-specific embryonic gene expression in species with newly evolved sex chromosomes. [PDF]
PLoS Genetics, 2014 Sex chromosome dosage differences between females and males are a significant form of natural genetic variation in many species. Like many species with chromosomal sex determination, Drosophila females have two X chromosomes, while males have one X and ...
Susan E Lott +4 more
doaj +1 more source
No evidence for a global male-specific lethal complex-mediated dosage compensation contribution to the demasculinization of the Drosophila melanogaster X chromosome. [PDF]
PLoS ONE, 2014 In Drosophila melanogaster males, the expression of X-linked genes is regulated by mechanisms that operate on a chromosomal scale. One such mechanism, male-specific lethal complex-dependent X-linked dosage compensation, is thought to broadly enhance the ...
Steven P Vensko, Eric A Stone
doaj +1 more source
Scientific Reports, 2021 In mammals, dosage compensation of X-linked gene expression between males and females is achieved by inactivation of a single X chromosome in females, while upregulation of the single active X in males and females leads to X:autosome dosage balance ...
Ana Luíza Cidral +3 more
doaj +1 more source