Results 41 to 50 of about 30,395 (278)

SU(VAR)3-7 links heterochromatin and dosage compensation in Drosophila. [PDF]

PLoS Genetics, 2008
In Drosophila, dosage compensation augments X chromosome-linked transcription in males relative to females. This process is achieved by the Dosage Compensation Complex (DCC), which associates specifically with the male X chromosome.
Anne Spierer, Flora Begeot, Pierre Spierer, Marion Delattre   +3 more
doaj   +1 more source

The evolution of dosage-compensation mechanisms [PDF]

BioEssays, 2000
Dosage compensation is the process by which the expression levels of sex-linked genes are altered in one sex to offset a difference in sex-chromosome number between females and males of a heterogametic species. Degeneration of a sex-limited chromosome to produce heterogamety is a common, perhaps unavoidable, feature of sex-chromosome evolution ...
I, Marín, M L, Siegal, B S, Baker
openaire   +2 more sources

Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation. [PDF]

PLoS Genetics, 2016
Dosage compensation is an essential process that equalizes transcript levels of X-linked genes between sexes by forming a domain of coordinated gene expression.
Guray Kuzu, Emily G Kaye, Jessica Chery, Trevor Siggers, Lin Yang, Jason R Dobson, Sonia Boor, Jacob Bliss, Wei Liu, Gerwald Jogl, Remo Rohs, Nadia D Singh, Martha L Bulyk, Michael Y Tolstorukov, Erica Larschan   +14 more
doaj   +1 more source

Global Analysis of the Relationship between JIL-1 Kinase and Transcription [PDF]

, 2010
The ubiquitous tandem kinase JIL-1 is essential for Drosophila development. Its role in defining decondensed domains of larval polytene chromosomes is well established, but its involvement in transcription regulation has remained controversial.
Regnard Catherine, Peter B Becker, Mitterweger Angelika, Ina K. Dahlsveen, Becker Peter B., Tobias Straub, Straub, Tobias, Peter B, Regnard, Catherine, Fabian Viola, Mitterweger, Angelika, Ina K Dahlsveen, Peter B. Becker, Dahlsveen Ina K., Becker, Peter B., Fabian, Viola, Dahlsveen, Ina K., Catherine Regnard, Angelika Mitterweger, Viola Fabian, Straub Tobias   +20 more
core   +1 more source

X-to-autosome expression and msl-2 transcript abundance correlate among Drosophila melanogaster somatic tissues [PDF]

PeerJ, 2015
In Drosophila melanogaster, the male-specific lethal (MSL) complex has been studied extensively for its role in upregulating male X-linked genes. Recent advances in high-throughput technologies have improved our understanding of how the MSL complex ...
Steven P. Vensko II, Eric A. Stone
doaj   +2 more sources

Dosage Compensation Systems [PDF]

, 2021
AbstractThis chapter provides an introduction to chromosome-wide dosage compensation systems. We will examine the evolution of dosage compensation, which is thought to be driven by the appearance of differentiated sex chromosomes. In a subset of species with X chromosomal sex determination or XY sex chromosome systems, expression of X-linked genes is ...
Renato Paro, Ueli Grossniklaus, Raffaella Santoro, Anton Wutz   +3 more
openaire   +1 more source

Sex chromosomes: Evolving dosage compensation [PDF]

, 1998
Dosage compensation of some X-linked genes varies among mammals. Inactivation of an X-linked copy of a gene in females appears to correlate with lack of an active homologue on the Y chromosome, implying that dosage compensation evolves in response to the
Charlesworth, Brian
core   +1 more source

Condensin-mediated chromosome organization and gene regulation

Frontiers in Genetics, 2015
In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene regulatory mechanism called dosage compensation equalizes X-linked gene expression between the ...
Alyssa Christine Lau, Gyorgyi eCsankovszki   +1 more
doaj   +1 more source

Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis.

PLoS Genetics, 2021
Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensation
Evan Witt, Zhantao Shao, Chun Hu, Henry M Krause, Li Zhao   +4 more
doaj   +1 more source

Relationship between dosage compensation and complex subunits. [PDF]

, 2017
Relationship between dosage compensation and complex subunits.
Koji Ishikawa (703501), Nicholas T. Ingolia (3697687), Hisao Moriya (63197), Koji Makanae (453303), Shintaro Iwasaki (3697684)   +4 more
core   +1 more source