Results 41 to 50 of about 30,369 (277)
Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation. [PDF]
PLoS Genetics, 2016 Dosage compensation is an essential process that equalizes transcript levels of X-linked genes between sexes by forming a domain of coordinated gene expression.
Guray Kuzu +14 more
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The evolution of dosage-compensation mechanisms [PDF]
BioEssays, 2000 Dosage compensation is the process by which the expression levels of sex-linked genes are altered in one sex to offset a difference in sex-chromosome number between females and males of a heterogametic species. Degeneration of a sex-limited chromosome to produce heterogamety is a common, perhaps unavoidable, feature of sex-chromosome evolution ...
I, Marín, M L, Siegal, B S, Baker
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Global Analysis of the Relationship between JIL-1 Kinase and Transcription [PDF]
, 2010 The ubiquitous tandem kinase JIL-1 is essential for Drosophila development. Its role in defining decondensed domains of larval polytene chromosomes is well established, but its involvement in transcription regulation has remained controversial.
Regnard Catherine +20 more
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X-to-autosome expression and msl-2 transcript abundance correlate among Drosophila melanogaster somatic tissues [PDF]
PeerJ, 2015 In Drosophila melanogaster, the male-specific lethal (MSL) complex has been studied extensively for its role in upregulating male X-linked genes. Recent advances in high-throughput technologies have improved our understanding of how the MSL complex ...
Steven P. Vensko II, Eric A. Stone
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Condensin-mediated chromosome organization and gene regulation
Frontiers in Genetics, 2015 In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene regulatory mechanism called dosage compensation equalizes X-linked gene expression between the ...
Alyssa Christine Lau +1 more
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Masc‐induced dosage compensation in silkworm cultured cells
FEBS Open Bio, 2019 The Masculinizer (Masc) gene encodes a CCCH‐tandem zinc finger protein that controls both masculinization and dosage compensation in the silkworm Bombyx mori.
Susumu Katsuma +4 more
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PLoS Genetics, 2021 Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensation
Evan Witt +4 more
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Genome biology, 2007 How the mechanisms of dosage compensation distinguish the sex chromosomes from the autosomes has been something of a mystery. A recent study in Caenorhabditis elegans has identified clusters of two common DNA motifs as a cis-acting code for the recruitment of the DCC, the protein complex that mediates dosage compensation.
Deng, Xinxian, Disteche, Christine M
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Dosage Compensation Systems [PDF]
, 2021 AbstractThis chapter provides an introduction to chromosome-wide dosage compensation systems. We will examine the evolution of dosage compensation, which is thought to be driven by the appearance of differentiated sex chromosomes. In a subset of species with X chromosomal sex determination or XY sex chromosome systems, expression of X-linked genes is ...
Renato Paro +3 more
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Mammalian X chromosome dosage compensation: Perspectives from the germ line
, 2021 Sex chromosomes are advantageous to mammals, allowing them to adopt a genetic rather than environmental sex determination system. However, sex chromosome evolution also carries a burden, because it results in an imbalance in gene dosage between females ...
Mahesh N Sangrithi (8907299) +1 more
core +1 more source