Results 61 to 70 of about 72,919 (193)
BMC Genomics, 2010 Background Considerable progress has been made in our understanding of sex determination and dosage compensation mechanisms in model organisms such as C. elegans, Drosophila and M. musculus.
Mathur Sachin +4 more
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Sequence Expression of Supernumerary B Chromosomes: Function or Fluff? [PDF]
, 2019 B chromosomes are enigmatic heritable elements found in the genomes of numerous plant and animal species. Contrary to their broad distribution, most B chromosomes are non-essential. For this reason, they are regarded as genome parasites.
Akbari, Omar S +2 more
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Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus
Epigenetics, 2023 The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA
Aleem Razzaq +4 more
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The status of dosage compensation in the multiple X chromosomes of the platypus. [PDF]
PLoS Genetics, 2008 Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XX females and XY males in therian mammals (marsupials ...
Janine E Deakin +3 more
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PLoS GeneticsDifferentiated sex chromosomes are frequently associated with major transcriptional changes: the evolution of dosage compensation (DC) to equalize gene expression between the sexes and the establishment of meiotic sex chromosome inactivation (MSCI).
Jelisaveta Djordjevic +11 more
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MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer
iScience, 2021 Summary: We hypothesize that dosage compensation of critical genes arises from systems-level properties for cancer cells to withstand the negative effects of aneuploidy.
ManSai Acón +16 more
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General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq
BMC Genomics, 2011 Background Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic XX/XY systems suggest that dosage compensation mechanisms are in place to ...
Wolf Jochen BW, Bryk Jarosław
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\u3cem\u3eAnolis\u3c/em\u3e Sex Chromosomes Are Derived from A Single Ancestral Pair [PDF]
, 2014 To explain the frequency and distribution of heteromorphic sex chromosomes in the lizard genus Anolis, we compared the relative roles of sex chromosome conservation versus turnover of sex‐determining mechanisms. We used model‐based comparative methods to
Gamble, Tony +3 more
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Expression in aneuploid Drosophila S2 cells.
PLoS Biology, 2010 Extensive departures from balanced gene dose in aneuploids are highly deleterious. However, we know very little about the relationship between gene copy number and expression in aneuploid cells.
Yu Zhang +6 more
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Expression of homoeologous molecular systems in wheat alloploids [PDF]
, 1976 Allopolyploidy is widespread in the plant kingdom, where it has been of considerable evolutionary significance. Although the existence of heterotic interactions between the genomes that make up an alloploid have been generally assumed, the precise nature
Aragoncillo Ballesteros, Cipriano +4 more
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