Results 61 to 70 of about 378,928 (303)
The role of ischemic preconditioning in gene expression related to inflammation in a rat model of intestinal ischemia-reperfusion injury [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To investigate the gene expression related to inflammation on mice subjected to intestinal ischemia and reperfusion (I/R) and treated with ischemic preconditioning (IPC).
Celina Teresa Castelo Branco Couto de Miranda +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Genetic alterations of CDX1, CYLD and CDKN2B genes in CRC
Journal of Current Oncology and Medical Sciences, 2021 Introduction: Colorectal cancer (CRC) is the third most frequent type of cancer in the world. In this explanation, genetic variation is associated in all cancers, particularly CRC, and modifications of numerous genes, such as CDX1, CYLD, and CDKN2B, are ...
Seyed Mohammad Taghi Hamidian +4 more
doaj
Kaohsiung Journal of Medical Sciences, 2020 Upregulation of lncRNA HOXA transcript at the distal tip (HOTTIP) plays important roles in cancer progression. Nevertheless, its functions in the growth and metastasis of ovarian carcinoma are unknown.
Hong Wu +2 more
doaj +1 more source
Differential conserted activity induced regulation of Nogo receptors (1-3), LOTUS and Nogo mRNA in mouse brain. [PDF]
PLoS ONE, 2013 Nogo Receptor 1 (NgR1) mRNA is downregulated in hippocampal and cortical regions by increased neuronal activity such as a kainic acid challenge or by exposing rats to running wheels.
Tobias E Karlsson +4 more
doaj +1 more source
Oncology Reports, 2017 Osteoarthritis (OA) is a degenerative disease characterized by deterioration of articular cartilage. The aim of this study was to identify and characterize the expression of microRNA-125b-5p (miR-125b-5p) in normal and OA synovial cells, and to determine its role in OA pathogenesis.
Feng-Xiao, Ge, Haitao, Li, Xin, Yin
openaire +3 more sources
Upregulation of PFKP and downregulation of FBP1 contribute to ER− breast cancers.
, 2013 ER− DE genes in the glycolysis/gluconeogenesis pathway are denoted in red for upregulation and in green downregulation. The red frame indicates the elevated anaerobic glycolysis subpathway in ER− cancers.
Bailiang Li (434697) +8 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
HeliyonBackground: Intestinal bacteria significantly contribute to the metabolism of intestinal epithelial tissues. As the occurrence and development of radiation enteritis (RE) depend on the “co-metabolism” microenvironment formed by the host and intestinal ...
Chen-ying Ma, Jing Zhao, Ju-ying Zhou
doaj +1 more source
Downregulation of PFKP and upregulation of FBP1 contribute to ER+ breast cancers.
, 2013 ER+ DE genes in the pentose phosphate pathway are denoted in red for upregulation and in green for downregulation. The red frame indicates the elevated oxidative subpathway of the pentose phosphate pathway in ER+ cancers.
Bailiang Li (434697) +8 more
core +1 more source