Results 61 to 70 of about 7,431,159 (264)
A novel approach to simulate gene-environment interactions in complex diseases [PDF]
, 2010 Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc ...
Amato, Roberto +24 more
core +1 more source
Cancer Informatics, 2018 Understanding gene-gene interaction and its causal relationship to protein-protein interaction is a viable route for understanding drug action at the genetic level, which is largely hindered by inability to robustly map gene regulatory networks. Here, we
Adel Aloraini, Karim M ElSawy
doaj +1 more source
Clinical pharmacology and therapy, 2020 Drug‐drug interactions (DDIs) and drug‐gene interactions (DGIs) are well known mediators for adverse drug reactions (ADRs), which are among the leading causes of death in many countries.
Jan-Georg Wojtyniak +3 more
semanticscholar +1 more source
Drug interactions and hepatotoxicity of clopidogrel [PDF]
, 2010 Clopidogrel (Plavix¨) is an antiplatelet drug, which is clinically used in combination with aspirin to reduce cardiovascular events in patients undergoing percutaneous coronary intervention or in patients suffering from acute coronary syndromes ...
Zahno, Anja-Christina
core +1 more source
Hospital drug safety - role of the pharmacists [PDF]
, 2005 Medication errors and adverse drug reactions are frequent in hospitalized patients. The principle aim of my dissertation was to review the existing data about frequency and risk factors of these findings and to propose measures for their reduction ...
Krähenbühl-Melcher, Anita Maria
core +1 more source
BMC Bioinformatics, 2023 This paper applies different link prediction methods on a knowledge graph generated from biomedical literature, with the aim to compare their ability to identify unknown drug-gene interactions and explain their predictions.
Fotis Aisopos, Georgios Paliouras
doaj +1 more source
Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition
Computational and Structural Biotechnology Journal, 2020 In recent decades the identification of pharmacogenomic gene-drug associations has evolved tremendously. Despite this progress, a major fraction of the heritable inter-individual variability remains elusive.
Yitian Zhou, Volker M. Lauschke
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Frontiers in Genetics, 2014 New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment.
Oscar Takeo Suzuki +12 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source