Results 21 to 30 of about 234,715 (258)
Annals of Internal Medicine: Clinical Cases, 2023 Drug-induced liver injury is a common cause of liver damage, with antimicrobial use as the leading cause. Although most patients recover after discontinuing the offending agent, severe cases may result in progressive disease or death, requiring liver ...
Makeda Dawkins +5 more
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Archives of Pathology & Laboratory Medicine, 2015 Context Drug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufactured or naturally occurring chemical compound. Drug-induced liver injury is of major concern owing to the ever increasing number of compounds introduced into the market for treatment of various ...
Kurt, Fisher +2 more
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Mechanisms of drug-induced liver injury [PDF]
The AAPS Journal, 2006 The idiosyncratic nature and poor prognosis of drug-induced liver injury (DILI) make this type of reaction a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The key to predicting and preventing DILI is understanding the underlying mechanisms.
Michael P, Holt, Cynthia, Ju
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Tuberculosis Drug-Induced Liver Injury
Jurnal Respirasi, 2020 Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO).
Soedarsono Soedarsono +1 more
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MicroRNAs in Drug-induced Liver Injury [PDF]
Journal of Clinical and Translational Hepatology, 2014 Drug-induced liver injury (DILI) is a leading cause of acute liver failure, and a major reason for the recall of marketed drugs. Detection of potential liver injury is a challenge for clinical management and preclinical drug safety studies, as well as a great obstacle to the development of new, effective and safe drugs.
Li, Li-Min, Wang, Dong, Zen, Ke
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Drug-Induced Liver Injury Induced by Bioflavonoids [PDF]
Cureus, 2021 Drug-induced liver injury (DILI) is a relatively rare disease with a vast spectre of clinical manifestations. Its diagnosis is based on the exclusion of other causes of liver disease. The identification of a causal agent is based on the temporal relation between the symptoms and their resolution after stopping the suspected drug.
Pais, João P +4 more
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Drug-Induced Liver Injuries (Clinical Guidelines for Physicians)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2019 Aim. Clinical guidelines for the management of adult patients suffering from drug-induced liver injuries (DILI) are intended for all medical specialists, who treat such patients in their clinical practice.Key findings.
Vladimir T. Ivashkin +8 more
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Case series and review of Ayurvedic medication induced liver injury
BMC Complementary Medicine and Therapies, 2021 Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002.
Christopher M. Karousatos +3 more
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Rational choice of hepatoprotectors for drug-induced liver injury
Gastroenterologìa, 2022 The article deals with a review of the current literature on the clinical use of hepatoprotectors in drug-induced liver injury. The literature was searched in Scopus, Web of Science, PubMed and other databases. Risk factors, pathogenetic mechanisms of li
H.V. Osyodlo +2 more
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Annals of Hepatology, 2019 Introduction and aim: Epidemiological information regarding drug-induced liver injury in some Latin American countries remains limited. Therefore, disease prevention and health promotion strategies are imperative to reduce drug-induced liver injuries and
Alejandra Cano-Paniagua +3 more
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