Results 31 to 40 of about 234,715 (258)

Dietary Intake of Vegetables and Cooking Oil Was Associated With Drug-Induced Liver Injury During Tuberculosis Treatment: A Preliminary Cohort Study

open access: yesFrontiers in Nutrition, 2021
Background and Purpose: Drug-induced liver injury is challenging during tuberculosis treatment. There is no epidemiological data investigating the relation between dietary intake and the risk of drug-induced liver injury during tuberculosis treatment ...
Jinyu Wang   +6 more
doaj   +1 more source

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

open access: yesBengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy   +4 more
doaj   +1 more source

Ayurvedic Drug-Induced Liver Injury

open access: yesAmerican Journal of Gastroenterology, 2017
Drug induced liver injury is responsible for 50% of acute liver failure in developed countries. Ayurvedic and homeopathic medicine have been linked to liver injury. This case describes the first documented case of Punarnava mandur and Kanchnar guggulu causing drug induced liver injury. Drug induced liver injury may be difficult to diagnosis, but use of
Dalal, Kunal K   +2 more
openaire   +2 more sources

Drug induced liver injury: do we still need a routine liver biopsy for diagnosis today?

open access: yesAnnals of Hepatology, 2014
For the pathologist, the diagnosis of drug induced liver injury (DILI) is challenging, because histopathological features mimic all primary hepatic and biliary diseases, lacking changes that are specific for DILI.
Rolf Teschke, Christian Frenzel
doaj   +1 more source

Impact of Non-Alcoholic Simple Fatty Liver Disease on Antituberculosis Drug-Induced Liver Injury

open access: yesInfection and Drug Resistance, 2021
Yi-Hui Liu,1 Yan Guo,2 Hong Xu,1 Hui Feng,1 Dong-Ya Chen1 1Department of Digestive Hepatology, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, 310003, People’s Republic of China; 2Department of Gastroenterology, Hangzhou Third Hospital, Hangzhou ...
Liu YH, Guo Y, Xu H, Feng H, Chen DY
doaj  

Pharmacogenomics in Drug Induced Liver Injury

open access: yesCurrent Drug Metabolism, 2009
Drug-induced liver injury (DILI) is a severe adverse effect. The majority of DILI cases are idiosyncratic and several mechanisms have been postulated to explain why some subjects develop DILI with drugs that are safe for the majority of individuals. Major mechanisms proposed for DILI are based on the production of reactive metabolites, immune-mediated ...
Andrade-Bellido, Raúl Jesús   +5 more
openaire   +4 more sources

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity

open access: yesToxins
Colchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang   +5 more
doaj   +1 more source

Evaluation of drug-induced liver injury as etiology for acute liver failure in Brazil

open access: yesAnnals of Hepatology, 2021
Introduction and objectives: Little is known about the etiology of acute liver failure (ALF) in Latin America. The objective of this paper is to investigate the main etiologies of ALF in Brazil, including Drug Induced Liver Injury (DILI) using stringent ...
Genario Santos   +15 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Safety of drugs

open access: yesРепродуктивная эндокринология, 2018
Liver is the main organ that plays an important role in the biotransformation of medicine in human body. Therefore, drug-induced liver injuries are much more common than official medical statistics show in different countries and on different continents.
А. А. Суханова   +2 more
doaj   +1 more source

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