Results 41 to 50 of about 401,429 (294)

Drug induced liver injury: do we still need a routine liver biopsy for diagnosis today?

Annals of Hepatology, 2014
For the pathologist, the diagnosis of drug induced liver injury (DILI) is challenging, because histopathological features mimic all primary hepatic and biliary diseases, lacking changes that are specific for DILI.
Rolf Teschke, Christian Frenzel
doaj   +1 more source

Impact of Non-Alcoholic Simple Fatty Liver Disease on Antituberculosis Drug-Induced Liver Injury

Infection and Drug Resistance, 2021
Yi-Hui Liu,1 Yan Guo,2 Hong Xu,1 Hui Feng,1 Dong-Ya Chen1 1Department of Digestive Hepatology, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, 310003, People’s Republic of China; 2Department of Gastroenterology, Hangzhou Third Hospital, Hangzhou ...
Liu YH, Guo Y, Xu H, Feng H, Chen DY
doaj  

Evaluation of drug-induced liver injury as etiology for acute liver failure in Brazil

Annals of Hepatology, 2021
Introduction and objectives: Little is known about the etiology of acute liver failure (ALF) in Latin America. The objective of this paper is to investigate the main etiologies of ALF in Brazil, including Drug Induced Liver Injury (DILI) using stringent ...
Genario Santos, Estela Regina Ramos Figueira, Luiz Augusto Carneiro D’Albuquerque, Paulo Bittencourt Lisboa, Marcio Dias de Almeida, Norma Arteiro Filgueira, Ilka Boin, Gilda Porta, Rita de Cássia Martins Alves da Silva, Cyntia Ferreira Gomes Viana, Luciana Costa Faria, Mario Reis Alvares-da-Silva, Adriano Claudio Pereira de Moraes, Daphne Benatti Goncalves Morsoletto, Liana Codes, Raymundo Paraná   +15 more
doaj   +1 more source

Xenobiotic metabolism: the effect of acute kidney injury on non-renal drug clearance and hepatic drug metabolism. [PDF]

, 2014
Acute kidney injury (AKI) is a common complication of critical illness, and evidence is emerging that suggests AKI disrupts the function of other organs.
Abosaif, Andres-Hernando, Andres-Hernando, Barbara Philips, Boucher, Bougle, Brown, Chan, Chawla, Chung, Doi, Dowling, Dreisbach, Dreisbach, English, Fadillioglu, Gardiner, Gertz, Golab, Group, Gurley, Hassoun, Heinemeyer, Heinemeyer, Iain MacPhee, Izuwa, John Dixon, Karim, Katie Lane, Kirwan, Kirwan, Klein, Kramer, Krueger, Kunihara, Kunuzova, Lane, Lash, Leblanc, Lee, Lee, Lohr, Martyn, Mastorakos, Meier-Hellmann, Michaud, Michaud, Miyazawa, Muntane-Relat, Murakami, Naud, Naud, Nicholson, Nolin, Nolin, Okabe, Okabe, Okabe, Owen, O’Shaunessy, Park, Park, Philips, Power, Schneider, Serteser, Shi, Shibata, Smith, Soni, Spapen, Srinivas, Sun, Tanabe, Tian, Venkatesh, Wang, Whelton, Wilkinson, Wilson, Yamaguchi, Yoshitani, Yu   +82 more
core   +2 more sources

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity

Toxins
Colchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang, Jingyi Duan, Wen Huang, Yan Cheng, Beiwei Zhu, Fei Li   +5 more
doaj   +1 more source

Safety of drugs

Репродуктивная эндокринология, 2018
Liver is the main organ that plays an important role in the biotransformation of medicine in human body. Therefore, drug-induced liver injuries are much more common than official medical statistics show in different countries and on different continents.
А. А. Суханова, Ю. Н. Мельник, А. Б. Гордийчук   +2 more
doaj   +1 more source

Aseptic meningitis, hepatitis and cholestasis induced by trimethoprim/sulfamethoxazole: a case report

BMC Pediatrics, 2021
Background Drug-induced aseptic meningitis is a rare, but challenging diagnosis, most commonly reported with nonsteoroidal anti-inflammatory drugs (NSAIDs) and antibiotics.
J. A. A. van Asperdt, R. A. De Moor
doaj   +1 more source

Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review

Molecules, 2023
The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to damage from various factors such as viral infections, drug reactions, excessive alcohol consumption, and autoimmune diseases.
Xiaoyangzi Li, Ruyang Lao, Jiawei Lei, Yuting Chen, Qi Zhou, Ting Wang, Yingpeng Tong   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Esterified Anabolic Androgen-Induced Liver Injury in a Hepatitis C Virus-Positive Patient: A CaseReport

International Journal of Medical Students, 2015
Background: Cases of drug induced liver injury still perplex gastroenterologists due to its wide range of presentations that mimic acute and chronic liver conditions.
Kyrillus S. Shohdy, Rasmia M. El Gohary
doaj   +1 more source