Results 91 to 100 of about 73,913 (251)

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Diagram of dsRNA injection analysis.

Experimental design for dsRNA injection analysis. Male last instar nymphs (N6 stage) were obtained from a mature colony, and dsRNA injection was performed in each individual.
Satoshi Miyazaki (19187), Kokuto Fujiwara (12962399), Kiyoto Maekawa (464704)   +2 more
core   +1 more source

The first RNAi‐based biopesticide approved in the United States: regulatory implications for the European Union – the case of Ledprona (Calantha™)

Pest Management Science, EarlyView.
The approval of the RNA interference‐based biopesticide Ledprona (Calantha™) in the USA marks a milestone for RNA‐based crop protection. We discuss the regulatory implications for the European Union, highlighting opportunities, challenges, and the need for adapted risk assessment frameworks for RNA‐based plant protection products.
Aline Koch, Gabi Krczal
wiley   +1 more source

Exogenous dsRNA triggers sequence-specific RNAi and fungal stress responses to control Magnaporthe oryzae in Brachypodium distachyon

Communications Biology
In vertebrates and plants, dsRNA plays crucial roles as PAMP and as a mediator of RNAi. How higher fungi respond to dsRNA is not known. We demonstrate that Magnaporthe oryzae (Mo), a globally significant crop pathogen, internalizes dsRNA across a broad ...
Ying Zheng, Benjamin Moorlach, Desiree Jakobs-Schönwandt, Anant Patel, Chiara Pastacaldi, Stefan Jacob, Ana R. Sede, Manfred Heinlein, Minna M. Poranen, Karl-Heinz Kogel, Maria Ladera Carmona   +10 more
doaj   +1 more source

Utilization of Bacteriophage phi6 for the Production of High-Quality Double-Stranded RNA Molecules

Viruses
Double-stranded RNA (dsRNA) molecules are mediators of RNA interference (RNAi) in eukaryotic cells. RNAi is a conserved mechanism of post-transcriptional silencing of genes cognate to the sequences of the applied dsRNA.
Alesia A. Levanova, Minna M. Poranen
doaj   +1 more source

Early grower perceptions and likely acceptance of RNAi‐based biopesticides in Australia

Pest Management Science, EarlyView.
Individual decisions on the adoption of RNAi‐based biopesticides reflect balance of perceived risks and benefits. Adoption can be facilitated through tailored communication strategies highlighting clear scientific evidence of product efficacy. Abstract BACKGROUND Managing pest resistance while reducing reliance on conventional chemical pesticides ...
Raquel Tardin‐Coelho, Julian Clifton, Peta Ashworth   +2 more
wiley   +1 more source

Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells

BMC Immunology, 2011
Background Pattern recognition receptors (PRRs) for double-stranded RNA (dsRNA) are components of innate immunity that recognize the presence of viral infection and initiate efficient defense mechanisms.
Tsao Ming-Sound, Yun James J, Der Sandy D   +2 more
doaj   +1 more source

Chk1 activity and the GSI of P. monodon after dsRNA-Chk1 injection.

, 2018
(A) Chk1 activity after injection of dsRNA-Chk1 and dsRNA-GFP. Vertical bars represent the mean ± SD (n = 3 for each group). Significant differences from controls are denoted: *P P. monodon after injection of dsRNA-GFP, dsRNA-Chk1, or PBS.
Heizhao Lin (765431), Lihua Qiu (178071), Pengfei Wang (123133), Lulu Yan (3229812), Chao Zhao (253684), Shigui Jiang (5279066), Shu Wang (180520), Sigang Fan (772381), Bobo Xie (3433766)   +8 more
core   +1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

Pest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa, Thuanne Pires Ribeiro, Daniele Heloisa Pinheiro, Valdeir Junio Vaz Moreira, Luanna Pinheiro Alburquerque Freitas Bezerra, Júlia Moura Rosário Santana, Lays Antunes Teixeira, Maria Eugenia Lisei‐de‐Sa, Deyse Alexandra Rosero Alpala, Manoely Abreu Reis, Isabela Tristan Lourenço‐Tessutti, Leonardo Lima Pepino Macedo, Carolina Vianna Morgante, Maria Cristina Mattar Silva, Marcos Fernando Basso, Janice de Almeida‐Engler, Maria Fatima Grossi‐de‐Sa   +16 more
wiley   +1 more source

Research progress on immune mechanism and control strategy of dsRNA impurities in mRNA vaccine

Expert Review of Vaccines
Introduction Double-stranded RNA (dsRNA) is a key impurity of mRNA vaccines prepared by in vitro transcription (IVT) and is primarily transcribed by T7 RNA polymerase.
Xinjun Liu, Chaoying Hu, Qian He, Yu Bai, Xuanxuan Zhang, Zhihao Fu, Xiao Ma, Miao Xu, Zhenglun Liang, Qunying Mao   +9 more
doaj   +1 more source