Results 101 to 110 of about 73,913 (251)

A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA [PDF]

Capsidless yadokariviruses (members of the order Yadokarivirales) with (+)RNA genomes divert the capsid of their partner icosahedral double-stranded RNA (dsRNA) viruses in different families of the order Ghabrivirales into the replication site.
Hisano, Sakae, Kondo, Hideki, Fadli, Muhammad, Castón, José R., Novoa, Guy, Suzuki, Nobuhiro   +5 more
core   +1 more source

Oral RNAi reduces survival and grain loss in Rhyzopertha dominica, including phosphine‐resistant populations

Pest Management Science, EarlyView.
Oral delivery of dsRNA targeting essential genes reduces adult survival and grain damage in Rhyzopertha dominica, including highly phosphine‐resistant populations. These findings support RNAi as a complementary mode‐of‐action for resistance management and postharvest protection in stored‐grain systems. Abstract BACKGROUND Phosphine fumigation remains a
ZiHan Shen, Wei Chen, KangXu Wang
wiley   +1 more source

Protective Effects of Long Double-Stranded RNA with Different CpG Motifs against Miamiensis avidus and Viral Hemorrhagic Septicemia Virus (VHSV) Infections in Olive Flounder (Paralichthys olivaceus)

Fishes
The South Korean aquaculture industry has incurred considerable production losses due to various infectious diseases. Artificially synthesized polyinosinic–polycytidylic acid (poly I:C), structurally similar to double-stranded RNA (dsRNA) and cytidine ...
Hee-Jae Choi, Da-Yeon Choi, Jung-Jin Park, Hye Jin Jung, Bo-Seong Kim, Sung-Chul Hong, Jun-Hwan Kim, Yue Jai Kang   +7 more
doaj   +1 more source

The effect of dsRNA competition on RNAi knockdown efficiency.

, 2012
(A) Competitor dsRNA injected alone. (1) DsRed dsRNA. (2) Ubx dsRNA. (B) Competitor and reporter dsRNA co-injected at a 10 to 1 ratio. (1) DsRed dsRNA injected at 1 µg/µL (competitor). EGFP dsRNA injected at 0.1 µg/µL (reporter).
Yoshinori Tomoyasu (48231), Keita Miyata (124456), Susan J. Brown (19392), Sherry C. Miller (124453)   +3 more
core   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration

Nature Communications
The innate immune sensor PKR for double-stranded RNA (dsRNA) is critical for antiviral defense, but its aberrant activation by cellular dsRNA is linked to various diseases.
Sadeem Ahmad, Tao Zou, Jihee Hwang, Linlin Zhao, Xi Wang, Anton Davydenko, Ilana Buchumenski, Patrick Zhuang, Alyssa R. Fishbein, Diego Capcha-Rodriguez, Aaron Orgel, Erez Y. Levanon, Sua Myong, James Chou, Matthew Meyerson, Sun Hur   +15 more
doaj   +1 more source

Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths [PDF]

, 2020
The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune response to viral infection.
Lee, Deokro
core  

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Exogenous Application of IR-Specific dsRNA Inhibits Infection of Cucumber Green Mottle Mosaic Virus in Watermelon

Agronomy
Cucumber green mottle mosaic virus (CGMMV) represents a serious threat in the production of watermelon. Small RNAs facilitate a mechanism known as RNA interference (RNAi), which regulates gene expression.
Yanhui Wang, Liming Liu, Yongqiang Fan, Yanli Han, Zhiling Liang, Yanfei Geng, Fengnan Liu, Qinsheng Gu, Baoshan Kang, Chaoxi Luo   +9 more
doaj   +1 more source

Perfil transcricional de genes do sistema imune em litopenaeus vannamei desafiados com IMNV, após o silenciamento viral por RNAI [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2015A incidência de doenças virais tem implicado em significativas perdas ...
Justino, Emily Bruna
core