Results 81 to 90 of about 68,502 (270)
Bacterially Expressed dsRNA Causes Gene Silencing in EAB
, 2019 RNA interference (RNAi) is a naturally occurring, biological process in which RNA molecules inhibit gene expression or translation by neutralizing target mRNA molecules.
Rieske-Kinney, Lynne
core +1 more source
Organization of the dsRNA in CHIKV spherules.
, 2023 (A) Computational slice through a cryo-electron tomogram containing two CHIKV spherules at the plasma membrane. The right slice shows an overlay of the dsRNA tracing for one of the two spherules. Density is black. Scale bar, 25nm.
Lars-Anders Carlson (236630) +1 more
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang +12 more
wiley +1 more source
, 2023 Varroa destructor is a parasitic mite of honey bees and a major driver of honey bee colony losses. By feeding on the host’s body fluids, this obligate ectoparasite has a strong impact on honey bee physiology, causing the reduction of weight and ...
Alfonso Cacace +6 more
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Occupancy of the dsRNA within spherules.
, 2023 (A) Volume fraction of the dsRNA, assuming a radius of 1.2 nm and using individually measured spherule volumes measured in tomograms. Each dot represents one spherule and the bar shows the mean.
Lars-Anders Carlson (236630) +1 more
core +1 more source
BMEMat, EarlyView.This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen +12 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2018 An important step in the initiation of the innate immune response to virus infection is the recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic pattern recognition receptors (PRRs).
Elizabeth J. Mateer +2 more
doaj +1 more source
dsRNA analyzer: a bioinformatic tool for targeted dsRNA design in arthropods
The growing interest for environmentally safe and species-selective pest control strategies has positioned RNA interference (RNAi) as a promising mechanism for targeted pest suppression. An emerging strategy in this approach employs double stranded RNA (dsRNA) as the low-risk pesticide (LRP) of choice.
Andronis, Christos +2 more
openaire +2 more sources
STAR ProtocolsMammalian Dicer has been proved to be functional on double-stranded RNAs (dsRNAs) and involved in antiviral immunity or immune regulation. Here, we present a protocol for identifying Dicer as a dsRNA binding and cleaving factor to transfected dsRNA in cell lines, based on small RNA sequencing (RNA-seq) and dsRNA-immunoprecipitation (dsRNA-IP).
Yunpeng Dai +6 more
openaire +2 more sources