Results 161 to 170 of about 73,913 (251)

Development of a Droplet-Based RNA Interference Feeding Assay for Neonates of the Citrus Root Weevil Diaprepes abbreviatus. [PDF]

Arch Insect Biochem Physiol
Saini T, Killiny N.
europepmc   +1 more source

Live Fast, Die Old: Lowering Insulin Signalling During Development Can Speed Growth, Increase Reproduction and Lifespan, but Impair Environmental Sensing and Harm Offspring in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 11, November 2026.
Developmental reduction of insulin/IGF‐1 signalling via daf‐2 RNAi accelerates development, increases early reproduction, fitness, and lifespan in C. elegans, but compromises environmental sensing. Reduced IIS promotes inappropriate offspring dauer entry and delays recovery from developmental arrest.
Sara D. Irish, Annabel Kimberley, Peter Lenart, Hanne Carlsson, Anna Braybrooke, Benjamin Towbin, Simone Immler, Alexei A. Maklakov   +7 more
wiley   +1 more source

Delivery, Persistence, and Functional Response of dsRNA in Acyrthosiphon pisum: Progress and Remaining Barriers. [PDF]

Arch Insect Biochem Physiol
Merkel L, Vatanparast M, Will T, Erler S, Amari K.   +4 more
europepmc   +1 more source

Engineering Anaerobic Metabolic Branch Points to Control Carbon Allocation Between Wax Ester Synthesis and Succinate Accumulation in Euglena gracilis

Journal of Eukaryotic Microbiology, Volume 73, Issue 6, November/December 2026.
ABSTRACT Under anaerobic conditions, Euglena gracilis degrades paramylon and synthesizes wax esters (WEs) while accumulating succinate in the culture supernatant. Succinate can either be converted to succinyl‐CoA by succinyl‐CoA synthetase (SCS) and enter the propionyl‐CoA biosynthetic pathway or accumulate extracellularly.
Rikuto Oishi, Ryunosuke Katayama, Mitsuhiro Ueda, Tatsuji Sakamoto, Masami Nakazawa   +4 more
wiley   +1 more source

Research Progress on Target Gene Screening and the Precise Control Potential of <i>Diaphorina citri</i> Using RNA Interference. [PDF]

Insects
Ye L, He Z, Li X, Huang A, Zhou J, Yi L.
europepmc   +1 more source

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang, Nemanja Djokovic, Alexander Herr, Anna Wacker, Emily Swanson Hay, Daniel Santana, Amanda E. Hargrove, Harald Schwalbe, Katarina Nikolic, Frank Abendroth, Olalla Vázquez   +10 more
wiley   +1 more source

dsRNAscan maps human dsRNAome, revealing conservation, intermolecular dsRNA, and correlates of ADAR dependency. [PDF]

Mol Cell
Andrews RJ, Bass BL.
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, Volume 600, Issue 19, Page 2850-2873, October 2026.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Optimization of dsRNA Length and Target Position for Enhanced RNA Interference Efficiency Targeting the Chitinase Gene <i>MsChi2</i> in <i>Mythimna separata</i>. [PDF]

Insects
Bao W, Qiu Y, Zhao X, Sun D, Gao F.
europepmc   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, Volume 36, Issue 86, 26 October 2026.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source