Results 161 to 170 of about 68,502 (270)
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew +12 more
wiley +1 more source
Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy
Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1594-1604, June 2026.Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber +4 more
wiley +1 more source
The Fate of dsRNA in the Nucleus [PDF]
Cell, 2001 Zhang, Zuo, Carmichael, Gordon G.
openaire +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Pest Management Science, Volume 82, Issue 6, Page 5184-5194, June 2026.Gene‐specific double‐stranded RNAs effectively silence essential genes in the invasive citrus pest Delottococcus aberiae, leading to significant mortality through both microinjection and oral delivery. These results provide proof of concept for RNA interference‐based biopesticides as selective and sustainable tools for citrus integrated pest management.
Carolina Gallego‐Giraldo +6 more
wiley +1 more source
The SQSTM1/<i>p62</i> of Pacific White Shrimp (<i>Litopenaeus vannamei</i>) Is Involved in the Oxidative Stress Induced by Ammonia Exposure. [PDF]
Animals (Basel)Lu W +5 more
europepmc +1 more source
Removal of dsRNA byproducts using affinity chromatography
Double-stranded RNA (dsRNA) molecules are immunogenic byproducts of in vitro transcription of single-stranded RNA (ssRNA). Removal of dsRNA from ssRNA is difficult because the byproducts have similar sizes, sequences, and charges to the desired ssRNA ...
Senne Dillen +8 more
core +1 more source
Journal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.ABSTRACT The overuse of synthetic pesticides in agriculture has raised significant environmental and health concerns. Biopesticides have emerged as viable, environmentally compatible alternatives. However, recent comprehensive reviews integrating all biopesticide categories and emphasizing their contribution to synthetic‐pesticide‐free and health‐safe ...
Molalign Assefa +5 more
wiley +1 more source
Targeted Suppression of the Tomato Pathogen <i>Alternaria alternata</i> via Exogenous Application of Double-Stranded RNA. [PDF]
J Fungi (Basel)Suprun AR +7 more
europepmc +1 more source
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Wheat (Triticum aestivum L.) is a globally important cereal crop which provides ∼20% calories in human diet. Identifying genes and elucidating their functions is still challenging in wheat due to its large genome (∼16 Gb) with significant amount of repetitive elements.
Santosh Gudi +6 more
wiley +1 more source