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Identification of Mycoviruses by dsRNA Extraction

Mycoviruses exist in all major groups of fungi. With the continuous development of science and technology, the methods of studying viruses are constantly updated, and progressively mycoviruses have been discovered where most of these viruses are RNA viruses.
Yanfei, Wang   +2 more
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TLR3 Tolls for dsRNA

Science's STKE, 2001
Members of the Toll-like receptor (TLR) family appear to recognize molecular patterns found on pathogens. Alexopoulou et al. have found that double-stranded RNA (dsRNA), which can be associate with viral infection, is recognized by TLR3. DsRNA-treated HEK293 cells that expressed TLR3 showed increased activity of the
openaire   +2 more sources

dsRNA Genetic Elements

2001
RNAi and Cosuppression: Double-Stranded RNA as an Agent of Sequence-Specific Genetic Silencing in Animals and Plants, Jeffrey A. Norman and Mary K. Montgomery The Double-Stranded RNA-Activated Protein Kinase PKR, Randal J. Kaufman The Double-Stranded RNA Viruses of Saccharomyces Cerevisiae, Reed B. Wickner, Juan Carlos Ribas, and Anjanette Searfoss The
openaire   +1 more source

In search of critical dsRNA targets of ADAR1

Trends in Genetics
Recent studies have underscored the pivotal role of adenosine-to-inosine RNA editing, catalyzed by ADAR1, in suppressing innate immune interferon responses triggered by cellular double-stranded RNA (dsRNA). However, the specific ADAR1 editing targets crucial for this regulatory function remain elusive.
Erez Y. Levanon   +2 more
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A New Method to Isolate Total dsRNA

2014
When a diseased plant is suspected to be infected with unknown viruses, the approach of isolating double-stranded RNA (dsRNA) from diseased tissues and analyzing the sequence has been useful for detecting the viruses. This procedure owes its success to the majority of plant pathogenic viruses being RNA viruses, which accumulate dsRNAs as copies of ...
Go, Atsumi   +2 more
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dsRNA Delivery Service

Science's STKE, 2006
CD14 is a glycosylphosphatidylinositol (GPI)-anchored pattern recognition receptor that is involved in activation of Toll-like receptors (TLRs) at the cell surface (see Finberg and Kurt-Jones). For example, it binds to lipopolysaccharide (LPS) and viruses to present these foreign agents to TLR4 and TLR2, respectively. Lee et al.
openaire   +1 more source

Cellular origins of dsRNA, their recognition and consequences

Nature Reviews Molecular Cell Biology, 2021
Y Grace Chen, Sun Hur, Hur Sun
exaly  

Detection of dsRNA by Acridine Orange Staining

Acridine orange is a nucleic acid binding dye that emits green fluorescence when bound to double-stranded DNA or RNA and red fluorescence when bound to single-stranded DNA or RNA under ultraviolet light. This unique characterization allows it to be used for distinguishing or visualization of dsRNA.
Tingshuai, Ma, Yu, Zhao, Xiaofei, Cheng
openaire   +2 more sources

dsRNA-induced condensation of antiviral proteins modulates PKR activity

Proceedings of the National Academy of Sciences of the United States of America, 2022
Giulia A Corbet   +2 more
exaly  

Reoviridae [dsRNA]

2019
Oliver Gries, Thomas Ly
openaire   +1 more source

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