Results 261 to 270 of about 74,293 (296)

Microarray evidence for off target effects in tick RNA interference experiments, and the lack of strong correlation between DSRNA and antibody phenotypes in tick In vitro treatments for vaccine candidate screening

, 2011
Ala E. Tabor, M. Rodriguez-Valle, Sebastian Kurscheid, Roberto A. Barrero, Cedric Gondro, Paula Moolhuijzen, Jess A. T. Morgan, A. Bruyeres, B. Zhang, M. Bellgard   +9 more
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Protamine-Lipid-dsRNA Nanoparticles Improve RNAi Efficiency in the Fall Armyworm, Spodoptera frugiperda.

Journal of Agricultural and Food Chemistry, 2022
Developing safe and effective double-stranded RNA (dsRNA) delivery systems remains a major challenge for gene silencing, especially in lepidopteran insects. This study evaluated the protamine sulfate (PS)/lipid/dsRNA nanoparticle (NP) delivery system for
Ramesh Kumar Dhandapani, D. Gurusamy, S. R. Palli   +2 more
semanticscholar   +1 more source

New Frontiers in Pest Control: Chitosan Nanoparticles-Shielded dsRNA as an Effective Topical RNAi Spray for Gram Podborer Biocontrol.

ACS Applied Bio Materials, 2021
Chickpea pod borer, Helicoverpa armigera, displays resistance to chemical insecticides and transgenics. The potential nontransformative RNAi approach of specific gene silencing by mRNA breakdown through exogenous double-stranded (dsRNA) delivery to ...
Henry Kolge, K. Kadam, S. Galande, Vikram Lanjekar, V. Ghormade   +4 more
semanticscholar   +1 more source

The dsRNA viruses

Virus Research, 2004
The dsRNA viruses represent a large, diverse group of pathogens (affecting a very wide range of host species), several of which are of medical, veterinary or agricultural importance. Many of the icosahedral dsRNA viruses show striking structural and functional similarities that reflect the similar problems that they face replicating their dsRNA genomes
openaire   +2 more sources

Murine immunosuppression with mycoviral dsRNA

Immunopharmacology, 1982
The effect of three different size molecular weight species of mycoviral dsRNA on the immune response to sRBC was tested in C57Bl/6 mice. The various dsRNA species were extracted from electrophoresis polyacrylamide-agarose slab gels. Their molecular weights ranged from 1.0 x 10(6) daltons to 3.5 x 10(6) daltons.
C W, Hewitt, J P, Adler
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Receptor-dsRNA-Receptor

Science, 2008
Toll-like receptors recognize molecules associated with pathogens and initiate inflammatory responses. For example, Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA), an intermediate viral replication. The TLR3 ectodomain binds as a dimer to dsRNA, but the molecular basis for signaling remains unclear.
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dsRNA-protein interactions studied by molecular dynamics techniques. Unravelling dsRNA recognition by DCL1

Archives of Biochemistry and Biophysics, 2016
Double stranded RNA (dsRNA) participates in several biological processes, where RNA molecules acquire secondary structure inside the cell through base complementarity. The double stranded RNA binding domain (dsRBD) is one of the main protein folds that is able to recognize and bind to dsRNA regions. The N-terminal dsRBD of DCL1 in Arabidopsis thaliana (
Drusin, Salvador Iván, Suarez, Irina Paula, Gauto, Diego Fernando, Rasia, Rodolfo Maximiliano, Moreno, Diego Martin   +4 more
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A polymer/detergent formulation improves dsRNA penetration through the body wall and RNAi-induced mortality in the soybean aphid Aphis glycines.

Pest Management Science, 2019
BACKGROUND It is difficult to efficiently silence gene expression in some insects, probably because of the degradation of dsRNA by enzymes present in the gut and hemolymph post-oral feeding or body injecting of dsRNA.
Yang Zheng, Y. Hu, Shuo Yan, Hang Zhou, D. Song, Meizhen Yin, Jie Shen   +6 more
semanticscholar   +1 more source