Results 51 to 60 of about 13,638,973 (240)

Juvenile myoclonic epilepsy has hyper dynamic functional connectivity in the dorsolateral frontal cortex

NeuroImage: Clinical, 2019
Purpose: Characterize the static and dynamic functional connectivity for subjects with juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach.
Yanlu Wang, Ivanka Savic Berglund, Martin Uppman, Tie-Qiang Li   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

An Improved Dynamic Window Approach Based on Reinforcement Learning for the Trajectory Planning of Automated Guided Vehicles

IEEE Access
The traditional dynamic window approach (DWA) adopts the constant intervals for the sampling window, which limits the trajectory exploration possibility.
Da Jiang, Ling Du, Shuhui Li, Meijing Wang, Hongchao Zhang, Xiaole Chen, Yunlong Sun   +6 more
doaj   +1 more source

A Comparative Analysis of Windowing Approaches in Dense Sensing Environments

Proceedings, 2018
Windowing is an established technique employed within dense sensing environments to extract relevant features from sensor data streams. Among the established approaches of Explicit, Time-based and Sensor-Event based windowing, Dynamic windowing ...
Bronagh Quigley, Mark Donnelly, George Moore, Leo Galway   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

AUV Path Planning Based on the Flow Field Method and Dynamic Window Approach

IEEE Access
In order to improve the performance of Autonomous Underwater Vehicles (AUVs) in complex marine environments, efficient and reliable navigation strategies are deemed essential.
Xiang Gao, Duowei Jia, Xinghua Liu, Jiaxuan Du, Haibo Zhang   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Dynamic Window Approach Using GOA Search Algorithm for Collision Avoidance Based on Obstacle Trajectory Prediction

IEEE Access
Mobile robots not only need to navigate autonomously in complex environments, but also need to avoid collisions with dynamic obstacles, especially pedestrians. This paper realizes dynamic obstacles detection and state estimation algorithm with LiDAR data,
Yuan Liu, Lingyu Zhang, Jiasheng Liu, YingYing She, Birui Zhang, Feiyan Min   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A 3D dynamic window approach with receding horizon optimization for real-time UAV path planning

Complex & Intelligent Systems
Efficient and reliable path planning in complex three-dimensional (3D) environments remains a critical challenge for unmanned aerial vehicles (UAVs). Although the dynamic window approach (DWA) has demonstrated effectiveness in local planning, it suffers ...
Lingfeng Hu, Jianwei Ma, Shaofei Zang
doaj   +1 more source