Results 71 to 80 of about 13,638,973 (240)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Improved D3QN Intelligent Vehicle Path Planning Guided by the Dynamic Window Approach

Algorithms
To address the prevalent issues of slow convergence, low exploration efficiency, and large value estimation bias in traditional Deep Q-Networks for intelligent vehicle path planning, this paper proposes an improved Dueling Double Deep Q-Network (D3QN ...
Jiahui Na, Wensheng Wang
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Support vector machine with dynamic shifting window for continuous speech recognition [PDF]

, 2006
Support Vector Machine (SVM) is excellence in classification owing to its discriminative trait. Automatic speech recognition (ASR), amongst many areas in pattern recognition could well benefit from this phenomenon.
Salam, Md. Sah, Ahmad, Abdul Manan, Samaon, Den Fairol   +2 more
core  

A Dynamic Sliding Window Approach for Activity Recognition

, 2011
. Human activity recognition aims to infer the actions of one or more persons from a set of observations captured by sensors. Usually, this is performed by following a fixed length sliding window approach for the features extraction where two parameters ...
Javier Ortiz Laguna, Angel Garćıa Olaya, Angel García Olaya, Daniel Borrajo, Javier Ortiz   +4 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Window

, 2015
BACKGROUND Window contributes to the broad field of photography and the narrow field of site responsive artworks that address subjectivity and time. The peer community includes Ryan Gander (UK), Martin Creed (UK) and Roman Ondàk (SVK).
Laresa Kosloff (18029314)
core   +1 more source

Path Planning of Underground Robots via Improved A* and Dynamic Window Approach

Applied Sciences
This paper addresses the limitations of the A* algorithm in underground roadway path planning, such as proximity to roadway boundaries, intersection with obstacle corners, trajectory smoothness, and timely obstacle avoidance (e.g., fallen rocks, miners ...
Jianlong Dai, Yinghao Chai, Peiyin Xiong
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source