Results 111 to 120 of about 29,365 (193)

ITGA2B/ITGB3‐Related Macrothrombocytopenia Associated With Gain‐of‐Function Mutations in ITGA2B or ITGB3 Genes

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Glanzmann thrombasthenia (GT) is an inherited hemorrhagic disorder characterised by impaired platelet functions, manifested clinically as spontaneous bleeding. It is usually inherited in an autosomal recessive manner. Platelet dysfunction in patients with GT is caused by quantitative and/or qualitative deficiencies in αIIbβ3, which result from
Jiao Wu, Han Yan, Zijian Li, Yilin Zhu, Ruonan Shao, Honglei Xin, Tongyu Jia, Mengyu Ge, Lu Zhang, Suyu Jiang, Jianhua Mao, Jiansong Huang, Chao Fang, Xiaodong Xi, Xiaofeng Shi   +14 more
wiley   +1 more source

Cryo-ET and MD simulations reveal that dynein-2 is tuned for binding to the A-tubule of the ciliary doublet. [PDF]

EMBO J
He HK, Kubo S, Chen X, Lv QH, Kage A, Ichikawa M.   +5 more
europepmc   +1 more source

Defective I1 dynein in <i>Chlamydomonas</i> axonemes is epistatic to the RII-binding domain function of radial spoke protein 3 (RSP3) in the regulation of ciliary motility. [PDF]

MicroPubl Biol
Sebastian MJ, Solmonson A, Gaillard AR.
europepmc   +1 more source

NuMA and Ninein: Dynein Cargo-Adaptors Without a Classical Cargo. [PDF]

Cells
Guo K, Merdes A.
europepmc   +1 more source

Active fluctuations of cytoplasmic actomyosin networks facilitate dynein-driven transport. [PDF]

iScience
Torisawa T, Saito K, Furuta K, Kimura A.
europepmc   +1 more source

Structural diversity and unity amongst axonemal dynein assembly factors. [PDF]

J Cell Sci
Ren M, Jaleel SA, King SM, Mali GR.
europepmc   +1 more source

A Syd and RUFY dynein adaptor complex mediates axonal circulation of dense core vesicles. [PDF]

J Cell Biol
Lund VK, Chirco A, Caliari M, Larsen AH, Tang KT, Gether U, Madsen KL, Wierer M, Kjaerulff O.   +8 more
europepmc   +1 more source

Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity. [PDF]

Elife
Neiswender H, Pride JE, Veeranan-Karmegam R, Allen P, Neiswender G, Prabakar A, Hao C, Fan X, Gonsalvez GB.   +8 more
europepmc   +1 more source

A LisH-domain protein interaction map reveals a Lis1-ARIH2-dynein regulatory axis. [PDF]

iScience
Gupta D, Maddika S.
europepmc   +1 more source

The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions. [PDF]

Elife
Boda A, Balázs V, Nagy A, Hargitai D, Lippai M, Simon-Vecsei Z, Molnár M, Fürstenhoffer F, Juhász G, Lőrincz P.   +9 more
europepmc   +1 more source