Results 131 to 140 of about 5,717 (230)
Emulsion formation is associated with the soluble phase, while the presence of yeast cells enhances stability through a steric mechanism, with a protein‐to‐oil ratio greater than 1:10 required to prevent oil droplet coalescence. ABSTRACT This study explored the nutrient composition, protein profile, physicochemical and emulsifying properties of ...
Luca Amagliani +8 more
wiley +1 more source
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Delayed centrosome maturation causes asymmetric particle partitioning.
(A) Time series of dynein distribution with ∼1 hr time delay between the centrosome maturation (also see Movie S3). During the simulated duration of 3000 s, the number of microtubules organized by the dominant centrosome increases from 200 to 800.
Jennifer Lippincott-Schwartz (171711) +2 more
core +1 more source
TDP‐43 pathology is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Peptidyl‐prolyl cis–trans isomerase A (PPIA), a foldase and chaperone protein, modulates TDP‐43 function in an acetylation‐dependent manner. Here, we show that inhibition of lysine deacetylation with vorinostat (SAHA) increases PPIA acetylation and ...
Serena Scozzari +10 more
wiley +1 more source
The Long Haul: Microtubule Motors as the Essential Supply Line for Neuronal Longevity
To survive a lifetime, neurons depend on a high‐fidelity logistics network powered by microtubule motors. We explore how a broad spectrum of genetic defects in this machinery drive a devastating spectrum of neurodevelopmental and neurodegenerative diseases, including Hereditary Spastic Paraplegia (HSP), Charcot–Marie‐Tooth Type 2 (CMT2), and ...
Emma D. Turner, Alison E. Twelvetrees
wiley +1 more source
Assembly, structure and regulation of dyneins in cilia
Cilia are conserved cellular organelles with important roles in human physiology. Dyneins are a family of minus-end directed, microtubule motors that are crucial for cilia function.
Rompolas, Panteleimon
core +1 more source
Most Lepidopterans produce two distinct sperm types—nucleated eupyrene (fertile) and anucleate apyrene (non‐fertile), yet the genetic mechanisms governing this dimorphism remain poorly understood.
Hao Sun +5 more
doaj +1 more source
SummaryMicrotubule doublet (MTD) is the main skeleton of cilia/flagella. Many proteins, such as dyneins and radial spokes, bind to MTD, and generate or regulate force.
Shibata, Keitaro +5 more
core +1 more source
dissertationMolecular motors of kinesin and dynein families are responsible for various intracellular activities, from long distance movement of organelles, vesicles, protein complexes, and mRNAs to powering mitotic processes.
Hong, Weili
core
Microtubule-associated cargo transport, a central process governing the localization and movement of various cellular cargoes, is orchestrated by the coordination of two types of motor proteins (kinesins and dyneins), along with diverse adaptor and ...
Hye Seon Lee +6 more
doaj +1 more source

