Results 71 to 80 of about 18,529 (254)

Capillary HPLC Separation of Selected Neuropeptides [PDF]

, 2012
Neuropeptides play a pivotal role in brain and peripheral nervous system function. As high performance liquid chromatography (HPLC) becomes the central tool in the separation and characterization of peptide and protein samples, its selectivity ...
Yi, Ying
core  

Acetaldehyde involvement in ethanol's postabsortive effects during early ontogeny [PDF]

, 2013
Clinical and biomedical studies sustains the notion that early ontogeny is a vulnerable window to the impact of alcohol. Experiences with the drug during these stages increase latter disposition to prefer, use or abuse ethanol.
Abate, Paula, March, Samanta Mabel, Molina, Juan Carlos   +2 more
core   +1 more source

Viral risk factor for seizures: Pathobiology of dynorphin in herpes simplex viral (HSV-1) seizures in an animal model

Neurobiology of Disease, 2006
Up to 89% of patients with herpes simplex virus type-1 (HSV-1) encephalitis can have seizures. Possibly, viruses are environmental triggers for seizures in genetically vulnerable individuals. Inherited dynorphin promoter polymorphisms are associated with
Marylou V. Solbrig, Russell Adrian, Daniel Y. Chang, Guey-Chuen Perng   +3 more
doaj  

Electroacupuncture as a treatment for suspected trigeminal nerve‐mediated head‐shaking in 42 horses

Equine Veterinary Education, EarlyView.
Summary Background Electroacupuncture (EA) has been used successfully as a treatment for trigeminal nerve‐mediated head‐shaking (TMHS) in a small case series, but results from a larger number of cases are lacking. Objectives To retrospectively investigate the effectiveness of EA as a treatment for horses with TMHS.
B. Dunkel, G. L. Hildon, K. M. Coumbe, E. Busuttil, D. von Schweinitz, S. Devereux   +5 more
wiley   +1 more source

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning

Cell Reports, 2019
Summary: Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behaviors ...
Matthew B. Pomrenze, Simone M. Giovanetti, Rajani Maiya, Adam G. Gordon, Lauren J. Kreeger, Robert O. Messing   +5 more
doaj  

Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit

Cell Reports, 2016
Kappa opioid receptors (KORs) are involved in a variety of aversive behavioral states, including anxiety. To date, a circuit-based mechanism for KOR-driven anxiety has not been described.
Nicole A. Crowley, Daniel W. Bloodgood, J. Andrew Hardaway, Alexis M. Kendra, Jordan G. McCall, Ream Al-Hasani, Nora M. McCall, Waylin Yu, Zachary L. Schools, Michael J. Krashes, Bradford B. Lowell, Jennifer L. Whistler, Michael R. Bruchas, Thomas L. Kash   +13 more
doaj   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

The dopamine D1-D2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in basal ganglia

Frontiers in Neuroanatomy, 2011
Dopaminergic signaling within the basal ganglia has classically been thought to occur within two distinct neuronal pathways; the direct striatonigral pathway which contains the dopamine D1 receptor and the neuropeptides dynorphin and substance P, and the
Melissa L. Perreault, Melissa L. Perreault, Ahmed eHasbi, Ahmed eHasbi, Brian F. O'Dowd, Brian F. O'Dowd, Susan R. George, Susan R. George   +7 more
doaj   +1 more source

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol

Journal of Neuroendocrinology, EarlyView.
Abstract Evidence from both clinical and preclinical studies indicates that females experience a faster progression to drug addiction and more severe addiction‐related health effects compared with males. Estradiol (E2) plays a critical role in these sex differences.
Patricia Sinclair, Navdeep S. Dhanjal, E. Blair Towers, Wendy J. Lynch, Nadine Kabbani   +4 more
wiley   +1 more source

Substance P regulates puberty onset and fertility in the female mouse [PDF]

, 2015
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S., Gill, J.C., Kaiser, U.B., Maguire, C.A., Navarro, V.M., Simavli, Serap Aynur, Thompson, I.R., Wolfe, A.   +7 more
core   +1 more source