Results 31 to 40 of about 5,930 (239)

Percepción de los nefrólogos españoles sobre un problema antiguo no resuelto: Prurito asociado a la enfermedad renal crónica (Pa-ERC)

open access: yesNefrología, 2023
Resumen: Introducción: El prurito asociado a enfermedad renal crónica se define como la sensación desagradable que provoca la necesidad de rascarse en una parte del cuerpo o en todo en personas con enfermedad renal crónica, tras haberse descartado otras
Marian Goicoechea   +12 more
doaj   +1 more source

Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies

open access: yesFrontiers in Pharmacology, 2015
The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides (enkephalins, endorphins and dynorphins). The endogenous cannabinoid system comprises lipid neuromodulators (endocannabinoids), enzymes
Katia eBefort
doaj   +1 more source

Perception of Spanish nephrologists on an old unsolved problem: Pruritus associated with chronic kidney disease (CKD-aP)

open access: yesNefrología (English Edition), 2023
Introduction: Pruritus associated with chronic kidney disease is defined as the sensation of itching, in people with chronic kidney disease, in a one area or all over the body that causes the need to scratch, after having ruled out other dermatological ...
Marian Goicoechea   +12 more
doaj   +1 more source

An opioid-like system regulating feeding behavior in C. elegans [PDF]

open access: yes, 2015
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B.   +3 more
core   +3 more sources

Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization. [PDF]

open access: yesPLoS ONE, 2014
Dynorphins, endogenous opioid peptides that arise from the precursor protein prodynorphin (Pdyn), are hypothesized to be involved in the regulation of mood states and the neuroplasticity associated with addiction.
Ami Cohen   +7 more
doaj   +1 more source

THE ROLE OF NEUROTRANSMITTERS IN ALCOHOL DEPENDENCE: ANIMAL RESEARCH [PDF]

open access: yes, 1996
— Animal studies have demonstrated that alcohol changes neurotransrrutter concentrations in the brain. These changes in levels of dopamine, serotonin, ^aminobutync acid (GABA), endogenous opioid peptides, and noradrcnaline are associated with activation ...
Philippe De Witte
core   +1 more source

Opioid modulation of GABA release in the rat inferior colliculus [PDF]

open access: yes, 2004
Background: The inferior colliculus, which receives almost all ascending and descending auditory signals, plays a crucial role in the processing of auditory information.
Casalotti, SO   +7 more
core   +3 more sources

Orexin (Hypocretin) Neurons Contain Dynorphin [PDF]

open access: yesThe Journal of Neuroscience, 2001
Orexins (also called hypocretins) are peptide neurotransmitters expressed in neurons of the lateral hypothalamic area (LHA). Mice lacking the orexin peptides develop narcolepsy-like symptoms, whereas mice with a selective loss of the orexin neurons develop hypophagia and severe obesity in addition to the narcolepsy phenotype. These different phenotypes
T C, Chou   +11 more
openaire   +2 more sources

A functional polymorphism in the prodynorphin gene affects cognitive flexibility and brain activation during reversal learning.

open access: yesFrontiers in Behavioral Neuroscience, 2015
Whether the opioid system plays a role in the ability to flexibly adapt behavior is still unclear. We used fMRI to investigate the effect of a nucleotide tandem repeat (68-bp VNTR) functional polymorphism of the prodynorphin gene on cerebral activation ...
Mikhail eVotinov   +7 more
doaj   +1 more source

Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]

open access: yes, 2020
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core   +1 more source

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