Results 41 to 50 of about 13,602 (296)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Unlocking the Potential: Assessing the Influence of Electronic Human Resource Management on Innovative Performance, Productivity, and Cost Efficiency with Employee Satisfaction as a Key Mediator

JISR Management and Social Sciences & Economics
In recent years, human resources (HR) have taken on a new face with the advent of electronic human resource management, or e-HRM. The emergence of this new face of HR is a result of intranet and internet technology.
Faiz Ahmed, Hamza Hakim, Aqil Shakoor, Qassia Shoaib   +3 more
doaj   +1 more source

Reflecting on E-Recruiting Research Using Grounded Theory [PDF]

, 2010
This paper presents a systematic review of the e-Recruiting literature through a grounded theory lens. The large number of publications and the increasing diversity of publications on e-Recruiting research, as the most studied area within e-HRM ...
Furtmüller, Elfi, Wilderom, Celeste, Wolfswinkel, Joost   +2 more
core   +2 more sources

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

E-HRM framework for sustainable performance in higher education

Sustainable Futures
Integrating digital technology into human resource management (HRM) enhances sustainable performance in higher education and presents challenges to well-being and organizational culture.
Daniel Kisahwan, Deden Komar Priatna, Winna Roswinna, Alex Winarno, Deni Hermana   +4 more
doaj   +1 more source

Managing change – can HR software help? [PDF]

, 2015
With the pace of change in the HR and wider business environment seemingly becoming ever-faster, Human Resources teams have a real challenge on their hands to manage any resulting disruption.
Carmichael, Jan L., Greggains, Marc, Rivers, Liz, Tomkinson, Emma   +3 more
core  

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Antecedents of environmental sustainability based on E-HRM approach: An empirical investigation

Green Technologies and Sustainability
Human resources play a crucial role in fostering a positive work environment and organizational growth, with a shift towards Green HRM practices becoming essential for environmental sustainability.
Chetan Sharma, Shoeb Ahmad, Nisha, Sunil Kumar, Nisha Kumari, Reyaz Ahmad   +5 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

The Role of Labour Productivity in the Influence of E-HRM on Sustainability Performance with Organizational Agility as a Moderating Variable in MSMEs

Almana: Jurnal Manajemen dan Bisnis
In this era, technological advances benefit many aspects of work, including  Human Resources Management (HRM). Implementing E-HRM helps organizations improve efficiency, reduce paper waste, and support sustainability principles. The study aims to examine
Antony Sentoso, Junestin Junestin, Alden Nelson   +2 more
doaj   +1 more source