Results 51 to 60 of about 23,495 (266)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Research and learning environment: the role of the teacher [PDF]
, 2005 In this paper, starting from a didactical proposal about the introduction of the concept of natural number, already experienced in some primary school classes, we report about the subsequent reorganization of it in a new experience, quite different from ...
VACCARO, VIRGINIA
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Enhancing random forests performance in microarray data classification [PDF]
, 2013 Random forests are receiving increasing attention for classification of microarray datasets. We evaluate the effects of a feature selection process on the performance of a random forest classifier as well as on the choice of two critical parameters, i.e.
DESSI, NICOLETTA +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Complete integrability of information processing by biochemical reactions [PDF]
, 2016 Statistical mechanics provides an effective framework to investigate information processing in biochemical reactions. Within such framework far-reaching analogies are established among (anti-) cooperative collective behaviors in chemical kinetics, (anti-)
Agliari, Elena +3 more
core +3 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Educar em Revista, 2011 A apresentação trata da evolução da chamada psicologia da educação matemática no Brasil, traçando os temas e as linhas teóricas desenvolvidas pelo Grupo de Pesquisa em Psicologia e Educação Matemática (PSIEM) da FE/UNICAMP, surgido no final da década de ...
Márcia Regina Ferreira de Brito
doaj +1 more source
Revista Prática Docente, 2020 Resumo: O presente artigo trata-se de um recorte de dissertação de mestrado em Educação Matemática. O problema surge da análise de duas tendências que tratamos de articular, por um lado os dados indicam eventuais falhas no aprendizado da matemática e por
Martielle Soledade Souza Santos +1 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source