Results 11 to 20 of about 21,662,479 (296)

Affinity, Kinetics, and Thermodynamics of E-selectin Binding to E-selectin Ligand-1 [PDF]

Journal of Biological Chemistry, 2001
E-selectin is an endothelial adhesion molecule, which mediates the tethering and rolling of leukocytes on vascular endothelium. It recognizes the glycoprotein E-selectin ligand-1 (ESL-1) as a major binding partner on mouse myeloid cells. Using surface plasmon resonance, we measured the kinetics and affinity of binding of monomeric E-selectin to ESL-1 ...
Wild, M, Huang, M, Schulze-Horsel, U, Van Der Merwe, P, Vestweber, D   +4 more
openaire   +3 more sources

P-selectin glycoprotein ligand-1 forms dimeric interactions with E-selectin but monomeric interactions with L-selectin on cell surfaces. [PDF]

PLoS ONE, 2013
Interactions of selectins with cell surface glycoconjugates mediate the first step of the adhesion and signaling cascade that recruits circulating leukocytes to sites of infection or injury.
Yan Zhang, Ning Jiang, Veronika I Zarnitsyna, Arkadiusz G Klopocki, Rodger P McEver, Cheng Zhu   +5 more
doaj   +2 more sources

Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation [PDF]

Inflammation, 1994
E-selectin is an inducible endothelial adhesion molecule that binds neutrophils. E-selectin mRNA is not constitutively detectable in the lungs of rats. Intratracheal injection of LPS induces pulmonary E-selectin mRNA expression at 2-4 h. Intratracheal injection of LPS followed at 2 and 4 h by intravenous injection of mouse F(ab')2 or F(ab') anti-E ...
Collins, Tucker, Yi, Eunhee S., Guo, Kaizhi, Williams, James H., Steininger, Christina N., Welply, Joseph K., Keene, Jeffery L., Schmuke, Jon J., Ulich, Thomas R., Howard, Susan C., Remick, Daniel G., Yin, Songmei   +11 more
openaire   +4 more sources

Association between Endothelial Selectin (E-Selectin) Gene Polymorphisms and E-Selectin Level with Visceral Leishmaniais, in an ARMS-PCR Based Study [PDF]

Iranian Journal of Parasitology, 2008
Background: In the visceral leishmaniasis (VL), parasites reside in reticuluendothelial system, mainly in macrophages. Endothelial Selectin (E-selectin) might play an important role in leukocyte-endothelium interactions and inflammatory cell recruitment.
M Fallah, A Bazmani, A Bazmani
doaj   +2 more sources

Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells. [PDF]

iScience, 2023
E-selectin is expressed on endothelial cells in response to inflammatory cytokines and mediates leukocyte rolling and extravasation. However, studies have been hampered by lack of experimental approaches to monitor expression in real time in living cells.
Ogrodzinski L, Platt S, Goulding J, Alexander C, Farr TD, Woolard J, Hill SJ, Kilpatrick LE.   +7 more
europepmc   +2 more sources

Oxidative stress, microparticles, and E-selectin do not depend on HIV suppression

Biomedical Papers
Background. Oxidative stress and inflammation are considered predictors of diseases associated with aging. Markers of oxidative stress, inflammation, and endothelial activation were investigated in people with HIV on antiretroviral treatment to determine
Katerina Havlickova, Svatava Snopkova, Miroslav Pohanka, Radek Svacinka, David Vydrar, Petr Husa, Jirina Zavrelova, Filip Zlamal, Lenka Fabianova, Miroslav Penka, Petr Husa   +10 more
doaj   +2 more sources

E-Selectin Is Associated with Daytime and 24-Hour Diastolic Blood Pressure Variability in Type 2 Diabetes

Biomedicines, 2022
E-selectin is an endothelial cell adhesion molecule involved in vascular inflammation. Elevated E-selectin has been reported in patients with high blood pressure and diabetes.
Dana Mihaela Ciobanu, Cornelia Bala, Adriana Rusu, Gabriel Cismaru, Gabriela Roman   +4 more
doaj   +1 more source

Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. [PDF]

PLoS ONE, 2013
Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability ...
Jessica M Banks, Christine T Herman, Ryan C Bailey   +2 more
doaj   +1 more source

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Schenkat, Sonja, Kiefmann, Rainer, Dörger, Martina, Goetz, Alwin Eduard, Heckel, Kai   +4 more
core   +1 more source

Data_Sheet_1_E-Selectin-Overexpressing Mesenchymal Stem Cell Therapy Confers Improved Reperfusion, Repair, and Regeneration in a Murine Critical Limb Ischemia Model.docx

, 2022
AimsNovel cell-based therapeutic angiogenic treatments for patients with critical limb ischemia may afford limb salvage. Mesenchymal stem cells (MSCs) do not overexpress E-selectin; however, we have previously demonstrated the cell-adhesion molecule's ...
Roberta M. Lassance-Soares (12021782), Zhao-Jun Liu (168517), Yulexi Y. Ortiz (12021776), Roberto I. Vazquez-Padron (12021785), Omaida C. Velazquez (12021788), Yan Li (23143), Punam P. Parikh (12021779), Hongwei Shao (493627), Hallie J. Quiroz (12021770), Samantha F. Valencia (12021773)   +9 more
core   +1 more source